7-Hydroxy Loxapine (CAS 37081-75-7)
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7-Hydroxy loxapine is studied in the area of research relating to its role as a metabolite in chemical metabolism pathways. In biochemical research, this compound is utilized to understand the oxidative processes that occur with loxapine and similar compounds, as it is a product of their metabolism. Investigations involving 7-hydroxy loxapine often focus on the enzymatic pathways responsible for its formation, particularly those involving the cytochrome P450 system. By studying this hydroxylated metabolite, researchers can discern the specific enzymes that are involved in chemical metabolism, their kinetics, and how they contribute to the clearance of the parent compound from the body. Additionally, 7-hydroxy loxapine is used in analytical studies to develop more precise assays for monitoring chemical metabolism in various biological matrices.
7-Hydroxy Loxapine (CAS 37081-75-7) References
- Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS. | Wong, YC., et al. 2012. J Pharm Biomed Anal. 58: 83-93. PMID: 21993198
- Brain disposition and catalepsy after intranasal delivery of loxapine: role of metabolism in PK/PD of intranasal CNS drugs. | Wong, YC. and Zuo, Z. 2013. Pharm Res. 30: 2368-84. PMID: 23739987
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Hydroxy Loxapine, 2.5 mg | sc-490844 | 2.5 mg | $393.00 |