7-Hydroxy Granisetron Hydrochloride (CAS 133841-04-0)
Alternate Names:
7-Hydroxy-1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride
CAS Number:
133841-04-0
Molecular Weight:
364.87
Molecular Formula:
C18H24N4O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Hydroxy Granisetron Hydrochloride is a chemical compound classified among serotonin 5-HT3 receptor antagonists and is chemically akin to Granisetron. Research has been done into this compound′s various cellular effects, which include anti-inflammatory and analgesic actions, as well as the capacity to inhibit cancer cell growth in controlled, in vitro studies. Its role as a 5-HT3 receptor antagonist means it blocks serotonin from attaching to this receptor, thereby disrupting serotonin-dependent signaling pathways that play a part in a range of bodily functions. Its high selectivity for 5-HT3 receptors, however, has made it particularly useful for research into serotonin′s role in bodily processes.
7-Hydroxy Granisetron Hydrochloride (CAS 133841-04-0) References
- Development and validation of a sensitive liquid chromatographic-tandem mass spectrometric method for the simultaneous analysis of granisetron and 7-hydroxy granisetron in human plasma and urine samples: application in a clinical pharmacokinetic study in pregnant subject. | Zhao, Y., et al. 2016. Biomed Chromatogr. 30: 149-54. PMID: 26053159
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Hydroxy Granisetron Hydrochloride, 1 mg | sc-491343 | 1 mg | $366.00 | |||
7-Hydroxy Granisetron Hydrochloride, 10 mg | sc-491343A | 10 mg | $2517.00 |