Date published: 2025-10-15

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7-Hydroxy-4-methyl-3-coumarinylacetic acid (CAS 5852-10-8)

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Alternate Names:
4-Methylumbelliferone-3-acetic acid
Application:
7-Hydroxy-4-methyl-3-coumarinylacetic acid is a fluorescence probe and pH indicator
CAS Number:
5852-10-8
Molecular Weight:
234.20
Molecular Formula:
C12H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Hydroxy-4-methylcoumarin-3-acetic acid (HMCA) holds significant importance as a naturally occurring aromatic acid found in various sources. Its presence in nature and diverse applications make it a valuable compound for scientific research endeavors. Furthermore, 7-Hydroxy-4-methyl-3-coumarinylacetic acid can be encountered in certain food and beverage sources, including beer, tea, and coffee. Notably, 7-Hydroxy-4-methyl-3-coumarinylacetic acid is believed to act as an inhibitor of the enzyme cytochrome P450, which plays a pivotal role in drug metabolism. Moreover, it is thought to possess antioxidant properties, thereby potentially safeguarding cells against the damaging effects of free radicals.


7-Hydroxy-4-methyl-3-coumarinylacetic acid (CAS 5852-10-8) References

  1. Analysis of fluorescence quenching of coumarin derivatives by 4-hydroxy-TEMPO in aqueous solution.  |  Żamojć, K., et al. 2014. J Fluoresc. 24: 713-8. PMID: 24337873
  2. Dihydroxy-Substituted Coumarins as Fluorescent Probes for Nanomolar-Level Detection of the 4-Amino-TEMPO Spin Label.  |  Żamojć, K., et al. 2019. Int J Mol Sci. 20: PMID: 31382639
  3. Metabolites Profiling of Manilkara mabokeensis Aubrév Bark and Investigation of Biological Activities.  |  Worowounga, X., et al. 2022. Int J Anal Chem. 2022: 4066783. PMID: 35669910
  4. Fluorigenic method for the assay of proteinase activity with the use of 4-methylumbelliferyl-casein.  |  Khalfan, H., et al. 1983. Biochem J. 209: 265-7. PMID: 6342607

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Hydroxy-4-methyl-3-coumarinylacetic acid, 100 mg

sc-210625
100 mg
$109.00