Molecular structure of 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin, CAS Number: 185304-42-1
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin (CAS 185304-42-1)
Application:
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin is A major metabolite of Irinotecan
CAS Number:
185304-42-1
Molecular Weight:
518.56
Molecular Formula:
C28H30N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin is a potent inhibitor of topoisomerase I, an enzyme involved in DNA replication and transcription. 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin is a derivative of camptothecin, a alkaloid found in the bark and stem of the Camptotheca acuminata tree. By binding to the topoisomerase I-DNA complex, 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin prevents the re-ligation of DNA strands, leading to the accumulation of DNA breaks and ultimately cell death.
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin (CAS 185304-42-1) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin, 1 mg | sc-210613 | 1 mg | $393.00 |