7-Ethoxycoumarin-d5 (CAS 1189956-39-5)
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7-Ethoxycoumarin-d5 is a chemical compound that functions as a fluorescent substrate for cytochrome P450 enzymes. When introduced into cellular or molecular systems, this compound is metabolized by cytochrome P450 enzymes through a process known as O-deethylation. This enzymatic reaction results in the formation of a highly fluorescent product, which can be quantitatively measured to assess the activity of cytochrome P450 enzymes. 7-Ethoxycoumarin-d5 is used as a probe to study the induction or inhibition of cytochrome P450 enzymes. By serving as a substrate for these enzymes, 7-Ethoxycoumarin-d5 provides valuable insights into the metabolism and biotransformation of xenobiotics. Its interaction with cellular components, particularly cytochrome P450 enzymes, allows for the elucidation of metabolic pathways and the assessment of metabolism.
7-Ethoxycoumarin-d5 (CAS 1189956-39-5) References
- Mechanistic Understanding of the Synergistic Potential of Azole Fungicides in the Aquatic Invertebrate Gammarus pulex. | Rösch, A., et al. 2017. Environ Sci Technol. 51: 12784-12795. PMID: 28921992
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Ethoxycoumarin-d5, 50 mg | sc-217433 | 50 mg | $275.00 |