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7-Ethoxy-4-methylcoumarin (CAS 87-05-8)

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Alternate Names:
Ethyl 4-methylumbelliferyl ether
Application:
7-Ethoxy-4-methylcoumarin is a fluorophore used to monitor functional activity of cytochromes
CAS Number:
87-05-8
Purity:
≥95%
Molecular Weight:
204.22
Molecular Formula:
C12H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Ethoxy-4-methylcoumarin is a synthetic aromatic compound that has sparked interest in scientific research due to its promising biochemical properties. Notably, 7-Ethoxy-4-methylcoumarin has played a role in research related to enzyme inhibition. By binding to the active sites of enzymes, it effectively hinders their catalytic activity, leading to its relevance in understanding the effects of environmental toxins on cells. Its versatility has established 7-Ethoxy-4-methylcoumarin as a promising compound, propelling its exploration in the scientific community for potential applications in the field of science.


7-Ethoxy-4-methylcoumarin (CAS 87-05-8) References

  1. Analysis of fluorescence quenching of coumarin derivatives by 4-hydroxy-TEMPO in aqueous solution.  |  Żamojć, K., et al. 2014. J Fluoresc. 24: 713-8. PMID: 24337873
  2. Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism.  |  Shah, MB., et al. 2016. Mol Pharmacol. 89: 435-45. PMID: 26826176
  3. Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.  |  Liu, J., et al. 2016. Biochemistry. 55: 1997-2007. PMID: 26982502
  4. Simultaneous Determination of Coumarin and Its Derivatives in Tobacco Products by Liquid Chromatography-Tandem Mass Spectrometry.  |  Ren, Z., et al. 2016. Molecules. 21: PMID: 27834935
  5. 4-Hydroxy-7-methyl-3-phenylcoumarin Suppresses Aflatoxin Biosynthesis via Downregulation of aflK Expressing Versicolorin B Synthase in Aspergillus flavus.  |  Moon, YS., et al. 2017. Molecules. 22: PMID: 28468270
  6. Free Radical-Scavenging Capacities, Phenolics and Capsaicinoids in Wild Piquin Chili (Capsicum annuum var. Glabriusculum).  |  Moreno-Ramírez, YDR., et al. 2018. Molecules. 23: PMID: 30332792
  7. Dihydroxy-Substituted Coumarins as Fluorescent Probes for Nanomolar-Level Detection of the 4-Amino-TEMPO Spin Label.  |  Żamojć, K., et al. 2019. Int J Mol Sci. 20: PMID: 31382639
  8. Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans.  |  Li, H., et al. 2021. Pharmacol Res. 163: 105220. PMID: 33007422
  9. The Photoinitiators Used in Resin Based Dental Composite-A Review and Future Perspectives.  |  Kowalska, A., et al. 2021. Polymers (Basel). 13: PMID: 33540697
  10. Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain).  |  Bada, L., et al. 2023. Molecules. 28: PMID: 36615543
  11. Therapeutic Effects of Coumarins with Different Substitution Patterns.  |  Flores-Morales, V., et al. 2023. Molecules. 28: PMID: 36903660
  12. Bitter Odorants and Odorous Bitters: Toxicity and Human TAS2R Targets.  |  Margulis, E., et al. 2023. J Agric Food Chem. 71: 9051-9061. PMID: 37263600
  13. Induction of cytochrome P450 1A1 in rat liver slices by 7-ethoxycoumarin and 4-methyl-7-ethoxycoumarin.  |  Kuhn, UD., et al. 1998. Exp Toxicol Pathol. 50: 491-6. PMID: 9784028

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Ethoxy-4-methylcoumarin, 100 mg

sc-214401
100 mg
$31.00