Molecular structure of 7-Epi 10-Desacetyl Paclitaxel, CAS Number: 78454-17-8
7-Epi 10-Desacetyl Paclitaxel (CAS 78454-17-8)
Alternate Names:
10-Deacetyl-7-epi-taxol; 10-Deacetyl-7-epitaxol; 10-Desacetyl-7-epipaclitaxel; 7-Epi-10-deacetyltaxol; 7-epi-10-Deacetyltaxol; Ormosin VI
Application:
7-Epi 10-Desacetyl Paclitaxel is A paclitaxel impurity which may inhibit cancer cell growth.
CAS Number:
78454-17-8
Purity:
≥98%
Molecular Weight:
811.87
Molecular Formula:
C45H49NO13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Paclitaxel impurity and Paclitaxel related compound B. The compound has been isolated from Taxus yunnanensis and shown to have potential growth inhibitory activities against human cancer cells.
7-Epi 10-Desacetyl Paclitaxel (CAS 78454-17-8) References
- Biologically active taxol analogues with deleted A-ring side chain substituents and variable C-2' configurations. | Swindell, CS., et al. 1991. J Med Chem. 34: 1176-84. PMID: 1672157
- Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas. | Yu, C., et al. 2018. BMC Plant Biol. 18: 197. PMID: 30223770
- Omic analysis of the endangered Taxaceae species Pseudotaxus chienii revealed the differences in taxol biosynthesis pathway between Pseudotaxus and Taxus yunnanensis trees. | Yu, C., et al. 2021. BMC Plant Biol. 21: 104. PMID: 33622251
- Role of female-predominant MYB39-bHLH13 complex in sexually dimorphic accumulation of taxol in Taxus media. | Yu, C., et al. 2022. Hortic Res. 9: uhac062. PMID: 35769613
- Promotion of microtubule assembly in vitro by taxol. | Schiff, PB., et al. 1979. Nature. 277: 665-7. PMID: 423966
- Taxol binds to polymerized tubulin in vitro. | Parness, J. and Horwitz, SB. 1981. J Cell Biol. 91: 479-87. PMID: 6118377
- Comparative metabolomic analyses revealed the differential accumulation of taxoids, flavonoids and hormones among six Taxaceae trees | Yu, C., Zhan, X., Zhang, C., Xu, X., Huang, J., Feng, S.,.. & Wang, H. 2021. Scientia Horticulturae. 285: 110196.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Epi 10-Desacetyl Paclitaxel, 2.5 mg | sc-207169 | 2.5 mg | $320.00 |