7-Dehydrocholesterol CAS: 434-16-2
MF: C27H44O
MW: 384.64
A down-regulator of cholesterol synthesis.

7-Dehydrocholesterol (CAS 434-16-2)

7-Dehydrocholesterol | CAS 434-16-2 is rated 5.0 out of 5 by 2.
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Alternate Names: Provitamin D3
Application: 7-Dehydrocholesterol is a down-regulator of cholesterol synthesis
CAS Number: 434-16-2
Purity: ≥90%
Molecular Weight: 384.64
Molecular Formula: C27H44O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in chloroform, and ethyl acetate. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
150-151° C(anhydr)
Boiling Point :
493.74° C at 760 mmHg (Predicted)
Density :
1.00 g/cm3 (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
Optical Activity :
α20/D -116°, c = 1 in CHCl3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
FZ5650000
PubChem CID :
Merck Index :
14: 2867
MDL Number :
MFCD00003624
EC Number :
207-100-5
Beilstein Registry :
2224615

Download SDS (MSDS)

Certificate of Analysis

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7-Dehydrocholesterol (CAS 434-16-2)  Product Citations

See how others have used 7-Dehydrocholesterol (CAS 434-16-2). Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

PMID: # 34473504  Sofferman, DL.|Konar, A.|Mastron, JN.|Spears, KG.|Cisneros, C.|Smith, AC.|Tapavicza, E.|Sension, RJ.| et al. 2021. J Phys Chem B.

PMID: # 34409305  Trabelcy, B.|Gerchman, Y.|Sapir, A.| et al. 2021. STAR Protoc. 2: 100710.

PMID: # 26428672  Bahety, P. et al. 2015. Eur J Nutr.

PMID: # 32559444  Curr. Biol.

Citations 1 to 4 of 4 total
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Rated 5 out of 5 by from Su Su, W. et al. (PubMed 26098102) found that alleviating redox imbalance enhances 7-Dehydrocholesterol, a down-regulator of cholesterol synthesis, production in engineered Saccharomyces cerevisiae. -SCBT Publication Review
Date published: 2015-04-19
Rated 5 out of 5 by from 7 7-Dehydrocholesterol, was reported, in many articles, as a substrate that is converted to cholesterol via the 7-Dehydrocholesterol reductase enzyme. -SCBT Publication Review
Date published: 2015-04-19
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