Molecular structure of 7-Chlorothiokynurenic acid hydrochloride, CAS Number: 135025-56-8
7-Chlorothiokynurenic acid hydrochloride (CAS 135025-56-8)
Application:
7-Chlorothiokynurenic acid hydrochloride is an NMDA receptor antagonist acting at the glycine site
CAS Number:
135025-56-8
Molecular Weight:
276.2
Molecular Formula:
C10H6ClNO2S HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Chlorothiokynurenic acid hydrochloride is an NMDA receptor antagonist acting at the glycine site. More potent than the corresponding kynurenic acid analog.
7-Chlorothiokynurenic acid hydrochloride (CAS 135025-56-8) References
- Thiokynurenates: a new group of antagonists of the glycine modulatory site of the NMDA receptor. | Moroni, F., et al. 1991. Eur J Pharmacol. 199: 227-32. PMID: 1720099
- The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil. | Pellegrini-Giampietro, DE., et al. 1994. Neuroscience. 63: 701-9. PMID: 7898671
- A study of the dose dependency of a glycine receptor antagonist in focal ischemia. | Chen, J., et al. 1993. J Pharmacol Exp Ther. 267: 937-41. PMID: 8246170
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Chlorothiokynurenic acid hydrochloride, 5 mg | sc-202430 | 5 mg | $38.00 |