Molecular structure of 7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine, CAS Number: 286411-09-4
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine (CAS 286411-09-4)
CAS Number:
286411-09-4
Molecular Weight:
256.69
Molecular Formula:
C14H9N2OCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine is an Adenosine A1-R antagonist. 7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine is believed that the compound is able to interact with certain biological targets in order to exert its effects. Specifically, 7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine has been found to interact with certain enzymes, receptors, and ion channels in order to modulate their activity.
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine (CAS 286411-09-4) References
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- Pyrazolo-triazolo-pyrimidine derivatives as adenosine receptor antagonists: a possible template for adenosine receptor subtypes? | Baraldi, PG., et al. 2002. Curr Pharm Des. 8: 2299-332. PMID: 12369947
- 1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors. | Manera, C., et al. 2005. Bioorg Med Chem Lett. 15: 4604-10. PMID: 16099648
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- An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis. | Kälin, RE., et al. 2009. Blood. 114: 1110-22. PMID: 19478043
- An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells. | Zhu, W., et al. 2011. Mol Cancer Res. 9: 294-310. PMID: 21257818
- Adenosine receptors in health and disease. | Gessi, S., et al. 2011. Adv Pharmacol. 61: 41-75. PMID: 21586355
- Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. | Schulz, MM., et al. 2012. Proc Natl Acad Sci U S A. 109: E2665-74. PMID: 22949700
- Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis. | Desmet, CJ., et al. 2013. Proc Natl Acad Sci U S A. 110: 5139-44. PMID: 23483055
- Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. | Akbarzadeh, M., et al. 2022. Cell Chem Biol. 29: 1053-1064.e3. PMID: 34968420
Inhibitor of:
Adenosine A1-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine, 5 mg | sc-300073 | 5 mg | $416.00 |