7-Amino-3 chloromethyl-3-cephem-4-carboxylic Acid p-Methoxybenzyl Ester Hydrochloride (CAS 113479-65-5)

7-Amino-3 chloromethyl-3-cephem-4-carboxylic Acid p-Methoxybenzyl Ester Hydrochloride, a chemical compound, has been extensively researched for its potential applications in antimicrobial research and drug development. Its mechanism of action involves inhibition of bacterial cell wall synthesis by irreversibly binding to penicillin-binding proteins (PBPs), particularly those involved in cross-linking peptidoglycan, thereby disrupting the structural integrity of bacterial cell walls and leading to bacterial cell lysis. This mechanism makes it effective against a broad spectrum of Gram-positive and Gram-negative bacteria. In scientific research, this compound has been utilized as a tool to explain the molecular mechanisms underlying bacterial cell wall synthesis and antibiotic resistance. Additionally, it has served as a scaffold for the development of novel cephalosporin derivatives with improved pharmacokinetic properties and enhanced antimicrobial activity. Furthermore, research efforts have explored its potential synergistic effects in combination therapy regimens, aiming to overcome bacterial resistance mechanisms and enhance antimicrobial efficacy. Overall, this compound holds promise as a valuable asset in antimicrobial research, contributing to advancements in understanding bacterial physiology and the development of novel antimicrobial agents.