7α-Hydroxy-4-cholesten-3-one-d7 (CAS 3862-25-7 (unlabeled))

7α-Hydroxy-4-cholesten-3-one-d7 is a steroidal compound that plays a role in the biosynthesis of bile acids in the liver. It is an intermediate in the classic pathway of bile acid synthesis, where it is converted into cholic acid and chenodeoxycholic acid. It is formed from cholesterol through a series of enzymatic reactions, and its subsequent conversion into bile acids is vital for the digestion and absorption of dietary fats. 7α-Hydroxy-4-cholesten-3-one-d7 is involved in the regulation of cholesterol homeostasis, as it serves as a precursor for the production of bile acid. It has been used as a tracer in studies of bile acid metabolism, allowing to investigate the kinetics and regulation of bile acid synthesis in various physiological and pathological conditions. Its stable isotope-labeled form, 7α-Hydroxy-4-cholesten-3-one-d7, is particularly useful in these studies, as it can be distinguished from the endogenous compound and accurately quantified using mass spectrometry.