Molecular structure of 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, CAS Number: 300675-28-9
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS 300675-28-9)
Application:
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a CK2 inhibitor
CAS Number:
300675-28-9
Molecular Weight:
258.1
Molecular Formula:
C10H5Cl2NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Casein kinase 2 (CK2) is a threonine/serine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many tumors and proliferating tissues, which lends promise as an anti-cancer drug target. This chemical inhibits CK2 with an IC50 value of 0.8 µM (1).
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS 300675-28-9) References
1 Golub, A.G., Yakovenko, O.Y., Bdzhola, V.G., et al. Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2. J Med Chem 49 6443-6450 (2006).Inhibitor of:
Apoptosis.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1 mg | sc-223742 | 1 mg | $26.00 | |||
7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 5 mg | sc-223742A | 5 mg | $110.00 |