Date published: 2025-10-15

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7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (CAS 6272-55-5)

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Application:
7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is an oxygen compound used for research purposes
CAS Number:
6272-55-5
Purity:
98%
Molecular Weight:
272.34
Molecular Formula:
C20H16O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is an oxygen compound used for research purposes. 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is involved the activation of aryl hydrocarbon receptors (AhRs) and subsequent activation of downstream signaling pathways. Activation of AhRs by THB[a]P-7-ol can trigger the activation of transcription factors like NF-κB and AP-1, leading to the expression of genes involved in inflammation, cell proliferation, and apoptosis. Additionally, 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol can induce oxidative stress, which can cause DNA damage and activate DNA repair pathways.


7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol (CAS 6272-55-5) References

  1. Synthesis of (+/-)-trans-7,8-Dihydrodiol of 6-Fluoro-benzo[a]pyrene via Hydroxyl-Directed Regioselective Functionalization of Substituted Pyrene.  |  Zajc, B. 1999. J Org Chem. 64: 1902-1907. PMID: 11674280
  2. Recent Progress in the Use of N-Halo Compounds in Organic Synthesis  |  Veisi, H., Ghorbani-Vaghei, R., & Zolfigol, M. A. 2010. Organic Preparations and Procedures International. 43(6): 489-540.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol, 1 g

sc-257013
1 g
$219.00