Date published: 2026-4-4

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6′-Sialyllactose sodium salt (CAS 35890-39-2)

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Alternate Names:
6′-N-Acetylneuraminyl-D-lactose
Application:
6′-Sialyllactose sodium salt is a reference compound
CAS Number:
35890-39-2
Molecular Weight:
655.53
Molecular Formula:
C23H38NO19Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6′-Sialyllactose sodium salt is a fascinating compound primarily recognized for its role in mimicking the biological activities of natural sialic acid-containing oligosaccharides. This compound, often utilized in glycobiology research, acts by interacting with sialic acid-binding immunoglobulin-type lectins (Siglecs) and selectins, which are critical for understanding cell-cell communication, pathogen interaction, and immune response modulation. The sodium salt form enhances its solubility, making it more amenable for experimental applications in vitro. By serving as a model substrate, 6′-Sialyllactose sodium salt aids in dissecting the mechanistic pathways through which sialic acids influence developmental processes, neural networking, and contribute to the molecular architecture of the extracellular matrix. Its role extends to the study of microbial pathogenesis, where it simulates the sialylated structures targeted by pathogens, thus offering insights into the development of antimicrobial strategies. This compound is pivotal for researchers delving into the complex interplay between carbohydrates and biological recognition, providing a tool to unravel the subtleties of glycan-mediated biological processes.


6′-Sialyllactose sodium salt (CAS 35890-39-2) References

  1. A Pasteurella multocida sialyltransferase displaying dual trans-sialidase activities for production of 3'-sialyl and 6'-sialyl glycans.  |  Guo, Y., et al. 2014. J Biotechnol. 170: 60-7. PMID: 24291191
  2. Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors.  |  Horiguchi, Y., et al. 2017. Biosens Bioelectron. 92: 234-240. PMID: 28222368
  3. Toxicological evaluation of 6'-sialyllactose (6'-SL) sodium salt.  |  Gurung, RB., et al. 2018. Regul Toxicol Pharmacol. 95: 182-189. PMID: 29555556
  4. C-Glycosidation of Unprotected Di- and Trisaccharide Aldopyranoses with Ketones Using Pyrrolidine-Boric Acid Catalysis.  |  Johnson, S., et al. 2018. J Org Chem. 83: 4581-4597. PMID: 29595968
  5. Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway.  |  Liu, Y., et al. 2019. mBio. 10: PMID: 31064828
  6. Toxicological safety evaluation of the human-identical milk oligosaccharide 6'-sialyllactose sodium salt.  |  Phipps, KR., et al. 2019. J Appl Toxicol. 39: 1444-1461. PMID: 31389052
  7. Negatively Charged Yellow-Emitting 1-Aminopyrene Dyes for Reductive Amination and Fluorescence Detection of Glycans.  |  Savicheva, EA., et al. 2020. Angew Chem Int Ed Engl. 59: 5505-5509. PMID: 31895495
  8. Evaluation of 6'-Sialyllactose Sodium Salt Supplementation to Formula on Growth and Clinical Parameters in Neonatal Piglets.  |  Monaco, MH., et al. 2020. Nutrients. 12: PMID: 32283716
  9. Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6'-Sialyllactose in healthy adults.  |  Kim, JH., et al. 2022. Regul Toxicol Pharmacol. 129: 105110. PMID: 34958861
  10. Weighted analysis of 2'-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3'-sialyllactose, and 6'-sialyllactose concentrations in human milk.  |  Conze, DB., et al. 2022. Food Chem Toxicol. 163: 112877. PMID: 35304182
  11. Discrimination between sialic acid linkage modes using sialyllactose-imprinted polymers.  |  Mavliutova, L., et al. 2021. RSC Adv. 11: 22409-22418. PMID: 35480790
  12. Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2.  |  Saso, W., et al. 2022. PLoS Pathog. 18: e1010590. PMID: 35700214
  13. Safety of 6'-sialyllactose (6'-SL) sodium salt produced by derivative strains of Escherichia coli BL21 (DE3) as a novel food pursuant to Regulation (EU) 2015/2283.  |  , ., et al. 2022. EFSA J. 20: e07645. PMID: 36507098

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6′-Sialyllactose sodium salt, 10 mg

sc-221110
10 mg
$255.00