Molecular structure of 6β-Prostaglandin I1, CAS Number: 62770-50-7
6β-Prostaglandin I1 (CAS 62770-50-7)
Application:
6β-Prostaglandin I1 is a hydrolytically stable PGI2 analog
CAS Number:
62770-50-7
Molecular Weight:
354.5
Molecular Formula:
C20H34O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
A stable PGI2 analog resistant to hydrolysis in aqueous solutions. Has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 µM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2
6β-Prostaglandin I1 (CAS 62770-50-7) References
1 Whittle, B.J.R., Moncada, S., Whiting, F., et al. Carbacyclin - a potent stable prostacyclin analogue for the inhibition of platelet aggregation. Prostaglandins 19 605-627 (1980). 2 Blair, I.A., Hensby, C.N., MacDermot, J. Prostacyclin-dependent activOrdering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6β-Prostaglandin I1, 1 mg | sc-205164 | 1 mg | $60.00 | |||
6β-Prostaglandin I1, 5 mg | sc-205164A | 5 mg | $272.00 |