6α-Methylprednisone (CAS 91523-05-6)
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6α-Methylprednisone, a synthetic glucocorticoid, is widely recognized for its potent anti-inflammatory properties. It is a structural analog of prednisone, a naturally occurring corticosteroid. 6α-Methylprednisone has been instrumental in studying the impact of glucocorticoids on the immune system and investigating their role in inflammation regulation. In the realm of neuroscience, it has played a role in studying the effects of glucocorticoids on neuronal development and plasticity. The mechanism of action of 6α-Methylprednisone involves its binding to the glucocorticoid receptor (GR). Upon binding, the GR is activated, triggering a cascade of downstream signaling pathways. These pathways culminate in the suppression of pro-inflammatory cytokine production, inhibition of cell proliferation, and hindered cell migration.
6α-Methylprednisone (CAS 91523-05-6) References
- Lack of renal 11 beta-hydroxysteroid dehydrogenase type 2 at birth, a targeted temporal window for neonatal glucocorticoid action in human and mice. | Martinerie, L., et al. 2012. PLoS One. 7: e31949. PMID: 22359645
- In vitro bioassays to evaluate complex chemical mixtures in recycled water. | Jia, A., et al. 2015. Water Res. 80: 1-11. PMID: 25989591
- Balancing the Budget: Accounting for Glucocorticoid Bioactivity and Fate during Water Treatment. | Jia, A., et al. 2016. Environ Sci Technol. 50: 2870-80. PMID: 26840181
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6α-Methylprednisone, 10 mg | sc-207145 | 10 mg | $337.00 |