Molecular structure of 6α-Hydroxy Budesonide, CAS Number: 577777-51-6
6α-Hydroxy Budesonide (CAS 577777-51-6)
Alternate Names:
(6α,11β,16α)-16,17-[Butylidenebis(oxy)]-6,11,21-trihydroxypregna-1,4-diene-3,20-dione
Application:
6α-Hydroxy Budesonide is a metabolite of Budesonide
CAS Number:
577777-51-6
Molecular Weight:
446.53
Molecular Formula:
C25H34O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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6α-Hydroxy Budesonide represents a chemically modified derivative of Budesonide, a well-known corticosteroid that has seen widespread use in the management of inflammatory conditions. The introduction of a hydroxy group at the 6α position of the Budesonide molecule marks a significant alteration in its chemical structure, potentially influencing its pharmacokinetic properties, receptor affinity, and solubility. This structural modification is aimed at fine-tuning the molecule′s interaction with glucocorticoid receptors
6α-Hydroxy Budesonide (CAS 577777-51-6) References
- Identification of budesonide metabolites in human urine after oral administration. | Matabosch, X., et al. 2012. Anal Bioanal Chem. 404: 325-40. PMID: 22573060
- Discrimination of prohibited oral use from authorized inhaled treatment of budesonide in sports. | Matabosch, X., et al. 2013. Ther Drug Monit. 35: 118-28. PMID: 23318282
- Applications and challenges in using LC-MS/MS assays for quantitative doping analysis. | Wang, Z., et al. 2016. Bioanalysis. 8: 1307-22. PMID: 27241820
- Budesonide use and misuse in sports: Elimination profiles of budesonide and metabolites after intranasal, high-dose inhaled and oral administrations. | Coll, S., et al. 2020. Drug Test Anal. 12: 629-636. PMID: 31306564
- Is zebrafish (Danio rerio) water tank model applicable for the assessment of glucocorticoids metabolism? The budesonide assessment. | de Araujo, ALD., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1179: 122826. PMID: 34225244
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6α-Hydroxy Budesonide, 1 mg | sc-217403 | 1 mg | $1020.00 |