6-trans-12-epi Leukotriene B4 (CAS 71548-19-1)
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Leukotrienes comprise a family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors. 6-trans-12-epi Leukotriene B4 is a non-enzymatic hydrolysis product of LTA4. It was originally isolated from glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNL). This compound has been shown to be weakly chemotactic for PMNL, with about 20 times less potency than LTB4, and to have no effect on the aggregation response.
6-trans-12-epi Leukotriene B4 (CAS 71548-19-1) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-trans-12-epi Leukotriene B4, 25 µg | sc-205159 | 25 µg | $112.00 | |||
6-trans-12-epi Leukotriene B4, 50 µg | sc-205159A | 50 µg | $214.00 |