Molecular structure of 6′-Sialyllactose sodium salt, CAS Number: 157574-76-0
6′-Sialyllactose sodium salt (CAS 157574-76-0)
Alternate Names:
α-NeuNAc-(2→6)-β-D-Gal-(1→4)-D-Glc; 6′-N-Acetylneuraminyl-lactose sodium salt
CAS Number:
157574-76-0
Purity:
≥98%
Molecular Weight:
655.53
Molecular Formula:
C23H38NO19Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6′-Sialyllactose sodium salt is a sialoglycan compound that plays a significant role in glycobiology research. It is a trisaccharide consisting of sialic acid, galactose, and glucose, and is a naturally occurring component of human breast milk. In research applications, it is used to study the biological functions of oligosaccharides in neurodevelopment and immune response, as it′s believed to contribute to the beneficial effects of breast milk on infant health. Additionally, 6′-Sialyllactose sodium salt is utilized in the investigation of cell signaling pathways, particularly those involving sialic acid-binding immunoglobulin-type lectins (Siglecs), which are important for cell-cell interaction and communication. This compound also aids in the exploration of the gut microbiome, as it serves as a substrate for commensal bacteria, influencing their growth and activity.
6′-Sialyllactose sodium salt (CAS 157574-76-0) References
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- A Pasteurella multocida sialyltransferase displaying dual trans-sialidase activities for production of 3'-sialyl and 6'-sialyl glycans. | Guo, Y., et al. 2014. J Biotechnol. 170: 60-7. PMID: 24291191
- Modulating the regioselectivity of a Pasteurella multocida sialyltransferase for biocatalytic production of 3'- and 6'-sialyllactose. | Guo, Y., et al. 2015. Enzyme Microb Technol. 78: 54-62. PMID: 26215345
- Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors. | Horiguchi, Y., et al. 2017. Biosens Bioelectron. 92: 234-240. PMID: 28222368
- Sialic acid linkage differentiation of glycopeptides using capillary electrophoresis - electrospray ionization - mass spectrometry. | Kammeijer, GSM., et al. 2017. Sci Rep. 7: 3733. PMID: 28623326
- Toxicological evaluation of 6'-sialyllactose (6'-SL) sodium salt. | Gurung, RB., et al. 2018. Regul Toxicol Pharmacol. 95: 182-189. PMID: 29555556
- C-Glycosidation of Unprotected Di- and Trisaccharide Aldopyranoses with Ketones Using Pyrrolidine-Boric Acid Catalysis. | Johnson, S., et al. 2018. J Org Chem. 83: 4581-4597. PMID: 29595968
- Sialylated variants of lacto-N-tetraose exhibit antimicrobial activity against Group B Streptococcus. | Craft, KM., et al. 2019. Org Biomol Chem. 17: 1893-1900. PMID: 30229793
- Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway. | Liu, Y., et al. 2019. mBio. 10: PMID: 31064828
- Toxicological safety evaluation of the human-identical milk oligosaccharide 6'-sialyllactose sodium salt. | Phipps, KR., et al. 2019. J Appl Toxicol. 39: 1444-1461. PMID: 31389052
- Evaluation of 6'-Sialyllactose Sodium Salt Supplementation to Formula on Growth and Clinical Parameters in Neonatal Piglets. | Monaco, MH., et al. 2020. Nutrients. 12: PMID: 32283716
- Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6'-Sialyllactose in healthy adults. | Kim, JH., et al. 2022. Regul Toxicol Pharmacol. 129: 105110. PMID: 34958861
- Bifunctional hetero di-disc for broad-spectrum influenza neutralization. | Moon, S., et al. 2022. Nanomedicine. 44: 102587. PMID: 35863620
- Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3'-sialyllactose and 6'-sialyllactose. | Zhu, Y., et al. 2023. Biotechnol Adv. 62: 108058. PMID: 36372185
- Safety of 6'-sialyllactose (6'-SL) sodium salt produced by derivative strains of Escherichia coli BL21 (DE3) as a novel food pursuant to Regulation (EU) 2015/2283. | , ., et al. 2022. EFSA J. 20: e07645. PMID: 36507098
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6′-Sialyllactose sodium salt, 25 mg | sc-257003A | 25 mg | $138.00 | |||
6′-Sialyllactose sodium salt, 50 mg | sc-257003 | 50 mg | $214.00 | |||
6′-Sialyllactose sodium salt, 100 mg | sc-257003B | 100 mg | $275.00 | |||
6′-Sialyllactose sodium salt, 250 mg | sc-257003C | 250 mg | $469.00 | |||
6′-Sialyllactose sodium salt, 500 mg | sc-257003D | 500 mg | $780.00 |