6-Phosphogluconic acid tri(cyclohexylammonium) salt (CAS 108347-81-5)

6-Phosphogluconic acid tri(cyclohexylammonium) salt is a chemically modified form of 6-phosphogluconic acid, where three cyclohexylammonium groups are attached to enhance its solubility and stability in various solvents. This chemical modification plays a critical role in its use within biochemical research, particularly in studies related to enzymatic processes and metabolic pathways. This compound is primarily utilized in the investigation of the pentose phosphate pathway, a crucial metabolic route that generates NADPH and pentoses. 6-Phosphogluconic acid is a key intermediate in this pathway, and its modified tri(cyclohexylammonium) salt form is used to study the enzyme 6-phosphogluconate dehydrogenase under more controlled and reproducible conditions. Researchers benefit from its enhanced solubility, which allows for more accurate and consistent dosing in enzymatic assays and helps in the elucidation of enzyme kinetics and mechanisms. In addition to its role in fundamental enzymatic research, this compound aids in the study of cellular redox states. The production of NADPH by 6-phosphogluconate dehydrogenase is vital for maintaining the reducing environment needed in cells. By using this modified form of 6-phosphogluconic acid, researchers can explore the dynamics of NADPH generation and its impact on cellular processes such as biosynthesis and response to oxidative stress. Moreover, the use of this compound extends to materials science, where its buffer capabilities and stability are exploited in the synthesis of new polymeric materials and in the stabilization of biological preparations. This broad range of applications highlights its versatility and importance in scientific research beyond just biological systems.