6-O-Methylguanine (CAS 20535-83-5)
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6-O-Methylguanine is a modified purine base that is of significant interest in the field of molecular biology, particularly in studies related to DNA damage and repair. As an analog of the natural DNA base guanine, 6-O-Methylguanine is often used by researchers to investigate the biological consequences of alkylating agents, which can induce mutations by adding methyl groups to DNA. The presence of 6-O-Methylguanine in genomic DNA is a marker for certain types of chemical exposures, and it plays a key role in studies aimed at understanding the mechanisms of mutagenesis and carcinogenesis. Additionally, this compound is central to the study of the base excision repair pathway, a cellular mechanism that corrects DNA lesions. Scientists also utilize 6-O-Methylguanine to examine the specificity and efficiency of DNA methyltransferases, enzymes involved in the repair of alkylated DNA.
6-O-Methylguanine (CAS 20535-83-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-O-Methylguanine, 10 mg | sc-217374 | 10 mg | $206.00 |