Date published: 2025-10-21

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6-O-Methyl Guanosine (CAS 7803-88-5)

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Alternate Names:
2-Amino-6-methoxy-9-B-D-ribofuranosyl-9H-purine
Application:
6-O-Methyl Guanosine is a guanine derivative that acts as modulators of GTPases and modulator-resistant enzymes
CAS Number:
7803-88-5
Molecular Weight:
297.27
Molecular Formula:
C11H15N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-O-Methyl Guanosine (OMG) is a modified version of guanosine, a nucleoside present in nucleic acids. It undergoes a specific modification by adding a methyl group to the oxygen atom at the 2′ position of the sugar ring. This alteration plays a role in various biological processes and has been extensively investigated in laboratory applications. 6-O-Methyl Guanosine finds application in diverse scientific research fields, notably in the study of cell signaling and gene regulation. It has been employed to investigate the influence of DNA methylation on gene expression and the impact of methylation on mRNA stability. Additionally, researchers have utilized 6-O-Methyl Guanosine to explore the effects of methylation on the activity of enzymes involved in DNA replication and transcription. The precise mechanism by which 6-O-Methyl Guanosine operates is not yet entirely comprehended. However, it is hypothesized that the methyl group attached to the 2′ position of the sugar ring of 6-O-Methyl Guanosine interacts with DNA or RNA strands, consequently influencing the structure and function of nucleic acids. Furthermore, it is believed that 6-O-Methyl Guanosine may engage with specific proteins, affecting their activity in cellular processes.


6-O-Methyl Guanosine (CAS 7803-88-5) References

  1. Sustainable Flow-Synthesis of (Bulky) Nucleoside Drugs by a Novel and Highly Stable Nucleoside Phosphorylase Immobilized on Reusable Supports.  |  Benítez-Mateos, AI. and Paradisi, F. 2022. ChemSusChem. 15: e202102030. PMID: 34726353

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-O-Methyl Guanosine, 1 mg

sc-210544A
1 mg
$130.00

6-O-Methyl Guanosine, 50 mg

sc-210544B
50 mg
$140.00

6-O-Methyl Guanosine, 100 mg

sc-210544
100 mg
$220.00

6-O-Methyl Guanosine, 250 mg

sc-210544C
250 mg
$430.00

6-O-Methyl Guanosine, 500 mg

sc-210544D
500 mg
$533.00