Date published: 2025-10-21

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6-O-alpha-D-Maltosyl-beta-cyclodextrin (CAS 104723-60-6 (anhydrous))

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CAS Number:
104723-60-6 (anhydrous)
Molecular Weight:
1459.27
Molecular Formula:
C54H90O45
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-O-alpha-D-Maltosyl-beta-cyclodextrin, a modified cyclodextrin derivative, serves as a crucial tool in scientific research, particularly in the fields of chemistry, materials science, and biotechnology. Its mechanism of action revolves around its unique molecular structure, which consists of a cyclic arrangement of glucose units forming a truncated cone shape with a hydrophobic cavity. This cavity allows 6-O-alpha-D-Maltosyl-beta-cyclodextrin to encapsulate guest molecules, forming inclusion complexes through non-covalent interactions such as hydrogen bonding and hydrophobic interactions. Researchers leverage this property for various purposes, including drug delivery systems, encapsulation of bioactive compounds, and the separation and purification of biomolecules. Moreover, 6-O-alpha-D-Maltosyl-beta-cyclodextrin has demonstrated utility in the development of novel materials, such as nanoparticles and supramolecular assemblies, owing to its role as a versatile building block or scaffold. Additionally, its chiral nature facilitates applications in chiral separation and chromatography, enabling the resolution of enantiomers and stereoisomers in analytical and preparative chemistry. Through its distinctive properties and diverse applications, 6-O-alpha-D-Maltosyl-beta-cyclodextrin continues to advance scientific research across various disciplines.


6-O-alpha-D-Maltosyl-beta-cyclodextrin (CAS 104723-60-6 (anhydrous)) References

  1. Complexation of phenytoin with some hydrophilic cyclodextrins: effect on aqueous solubility, dissolution rate, and anticonvulsant activity in mice.  |  Latrofa, A., et al. 2001. Eur J Pharm Biopharm. 52: 65-73. PMID: 11438425
  2. Complex of branched cyclodextrin and lidocaine prolonged the duration of peripheral nerve block.  |  Suzuki, R., et al. 2009. J Anesth. 23: 295-7. PMID: 19444576
  3. Experimental and Theoretical Investigations on the Supermolecular Structure of Isoliquiritigenin and 6-O-α-D-Maltosyl-β-cyclodextrin Inclusion Complex.  |  Li, B., et al. 2015. Int J Mol Sci. 16: 17999-8017. PMID: 26247946
  4. Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins.  |  Fan, H., et al. 2017. Molecules. 22: PMID: 28230805
  5. Photoirradiation surface molecularly imprinted polymers for the separation of 6-O-α-d-maltosyl-β-cyclodextrin.  |  Fan, H., et al. 2017. J Sep Sci. 40: 4653-4660. PMID: 28985024
  6. Rational formulation engineering of fraxinellone utilizing 6-O-α-D-maltosyl-β-cyclodextrin for enhanced oral bioavailability and hepatic fibrosis therapy.  |  Li, J., et al. 2021. Drug Deliv. 28: 1890-1902. PMID: 34519225
  7. Inclusion Complex of Isoliquiritigenin With Sulfobutyl Ether-β-Cyclodextrin: Preparation, Characterization, Inclusion Mode, Solubilization, and Stability.  |  Wu, X., et al. 2022. Front Chem. 10: 930297. PMID: 35800032
  8. Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.  |  Yamada, Y., et al. 2022. Biomed Pharmacother. 155: 113698. PMID: 36116252

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-O-alpha-D-Maltosyl-beta-cyclodextrin, 1 g

sc-291409
1 g
$80.00

6-O-alpha-D-Maltosyl-beta-cyclodextrin, 5 g

sc-291409A
5 g
$250.00