Date published: 2026-3-13

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6-Methoxy-2-naphthaldehyde (CAS 3453-33-6)

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Application:
6-Methoxy-2-naphthaldehyde is a diagnostic reagent in tumor studies
CAS Number:
3453-33-6
Purity:
≥98%
Molecular Weight:
186.21
Molecular Formula:
C12H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Methoxy-2-naphthaldehyde is a non-steroidal antiinflammatory molecule belonging to the class of naphthalenes. 6-Methoxy-2-naphthalenecarboxaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. Shown to be a strong fluorescence probe.


6-Methoxy-2-naphthaldehyde (CAS 3453-33-6) References

  1. Aromatic aldehydes as fluorogenic indicators for human aldehyde dehydrogenases and oxidases: substrate and isozyme specificity.  |  Wroczyński, P. and Wierzchowski, J. 2000. Analyst. 125: 511-6. PMID: 10829347
  2. Alcohol and aldehyde dehydrogenase activity measured with fluorogenic substrates in the liver of rats poisoned with methanol.  |  Chrostek, L., et al. 2001. Exp Toxicol Pathol. 53: 77-80. PMID: 11370738
  3. The activity of class I, II, III, and IV alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in colorectal cancer.  |  Jelski, W., et al. 2004. Dig Dis Sci. 49: 977-81. PMID: 15309886
  4. Determination of human serum alcohol dehydrogenase using isozyme-specific fluorescent substrates.  |  Wierzchowski, J., et al. 1992. Anal Chem. 64: 181-6. PMID: 1616124
  5. Activities of cytosolic aldehyde dehydrogenase isozymes in colon cancer: determination using selective, fluorimetric assays.  |  Wroczyński, P., et al. 2005. Acta Pol Pharm. 62: 427-33. PMID: 16583981
  6. Development of a high-throughput screen for soluble epoxide hydrolase inhibition.  |  Wolf, NM., et al. 2006. Anal Biochem. 355: 71-80. PMID: 16729954
  7. A fluorogenic aldehyde bearing a 1,2,3-triazole moiety for monitoring the progress of aldol reactions.  |  Guo, HM. and Tanaka, F. 2009. J Org Chem. 74: 2417-24. PMID: 19222210
  8. Salivary aldehyde dehydrogenase - temporal and population variability, correlations with drinking and smoking habits and activity towards aldehydes contained in food.  |  Giebułtowicz, J., et al. 2010. Acta Biochim Pol. 57: 361-8. PMID: 20931090
  9. Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.  |  Bjelic, S., et al. 2014. J Mol Biol. 426: 256-71. PMID: 24161950
  10. Human Salivary Aldehyde Dehydrogenase: Purification, Kinetic Characterization and Effect of Ethanol, Hydrogen Peroxide and Sodium Dodecyl Sulfate on the Activity of the Enzyme.  |  Alam, MF., et al. 2016. Cell Biochem Biophys. 74: 307-15. PMID: 27324040
  11. Wavelength-tunable AIEgens based on 6-methoxy-2-naphthaldehyde: AIE behavior and bioimaging performance.  |  Zhao, Y., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 281: 121621. PMID: 35853254
  12. Serum class I and II alcohol dehydrogenase activity during the course of viral hepatitis.  |  Chrostek, L. and Szmitkowski, M. 1995. Eur J Clin Chem Clin Biochem. 33: 825-9. PMID: 8620059
  13. Selective assay of the cytosolic forms of the aldehyde dehydrogenase in rat, with possible significance for the investigations of cyclophosphamide cytotoxicity.  |  Wierzchowski, J., et al. 1996. Acta Pol Pharm. 53: 203-8. PMID: 8960290
  14. Fluorimetric detection of aldehyde dehydrogenase activity in human blood, saliva, and organ biopsies and kinetic differentiation between class I and class III isozymes.  |  Wierzchowski, J., et al. 1997. Anal Biochem. 245: 69-78. PMID: 9025970

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Methoxy-2-naphthaldehyde, 5 g

sc-233606
5 g
$93.00