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6-Mercaptohexanoic acid (CAS 17689-17-7)

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Alternate Names:
MHA
Application:
6-Mercaptohexanoic acid is a thiol alkyl acid for the preparation of gold nanoparticles
CAS Number:
17689-17-7
Molecular Weight:
148.22
Molecular Formula:
C6H12O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Mercaptohexanoic acid belongs to the family of carboxylic acids. One significant application of 6-Mercaptohexanoic acid is as a chemical intermediate in the synthesis of specialized compounds. It is used in the production of mercapto-based polymers, which find use in adhesive formulations, surface coatings, and elastomers. These polymers offer excellent adhesion, flexibility, and resistance to chemicals, making them suitable for diverse industrial applications. Another important use of 6-Mercaptohexanoic acid is in the field of analytical chemistry. It is employed as a reducing agent and stabilizer in certain types of chemical analyses, such as the determination of heavy metal ions. The thiol group of the acid can complex with metal ions, allowing their quantification in various samples. In addition, 6-Mercaptohexanoic acid has found applications in the preparation of self-assembled monolayers (SAMs) on surfaces. SAMs are molecular coatings formed by the adsorption of organic molecules onto a substrate, resulting in tailored surface properties. These modified surfaces are utilized in fields like sensors, catalysis, and biotechnology. In summary, 6-Mercaptohexanoic acid is a versatile compound used in the production of specialized polymers, as a reducing agent in analytical chemistry, and in the preparation of self-assembled monolayers. Its unique properties make it valuable in various industrial and scientific applications.


6-Mercaptohexanoic acid (CAS 17689-17-7) References

  1. Thiol-functionalized, 1.5-nm gold nanoparticles through ligand exchange reactions: scope and mechanism of ligand exchange.  |  Woehrle, GH., et al. 2005. J Am Chem Soc. 127: 2172-83. PMID: 15713095
  2. Effect of intramonolayer hydrogen bonding of carboxyl groups in self-assembled monolayers on a single force with phenylurea on an AFM probe tip.  |  Kado, S., et al. 2006. Anal Sci. 22: 521-7. PMID: 16760591
  3. Introducing amphiphilicity to noble metal nanoclusters via phase-transfer driven ion-pairing reaction.  |  Yao, Q., et al. 2015. J Am Chem Soc. 137: 2128-36. PMID: 25584784
  4. Investigation of Hemoglobin/Gold Nanoparticle Heterolayer on Micro-Gap for Electrochemical Biosensor Application.  |  Lee, T., et al. 2016. Sensors (Basel). 16: PMID: 27171089
  5. Synthesis of highly fluorescent gold nanoclusters and their use in sensitive analysis of metal ions.  |  Yang, Y., et al. 2017. Analyst. 142: 4486-4493. PMID: 29094138
  6. An ultrasensitive electrochemical impedance-based biosensor using insect odorant receptors to detect odorants.  |  Khadka, R., et al. 2019. Biosens Bioelectron. 126: 207-213. PMID: 30415156
  7. The influence of selected ω-mercaptocarboxylate ligands on physicochemical properties and biological activity of Cd-free, zinc‑copper‑indium sulfide colloidal nanocrystals.  |  Kalinowska, D., et al. 2019. Mater Sci Eng C Mater Biol Appl. 97: 583-592. PMID: 30678945
  8. Spectroscopic and electrophoresis study of substitution on the surface of gold nanoparticles by different mercaptoalkyl carboxylic acids and bioconjugation with bovine serum albumin.  |  Silveira, RL., et al. 2019. Anal Bioanal Chem. 411: 3047-3058. PMID: 30931504
  9. Real Time Monitoring of the Dynamic Intracluster Diffusion of Single Gold Atoms into Silver Nanoclusters.  |  Zheng, K., et al. 2019. J Am Chem Soc. 141: 18977-18983. PMID: 31609116
  10. Synergistic improvement in the performance of insect odorant receptor based biosensors in the presence of Orco.  |  Khadka, R., et al. 2020. Biosens Bioelectron. 153: 112040. PMID: 31989943
  11. Composition-Dependent Antimicrobial Ability of Full-Spectrum AuxAg25-x Alloy Nanoclusters.  |  Zheng, K. and Xie, J. 2020. ACS Nano. 14: 11533-11541. PMID: 32794730
  12. Biomimetic Self-Assembling Metal-Organic Architectures with Non-Iridescent Structural Coloration for Synergetic Antibacterial and Osteogenic Activity of Implants.  |  Zhang, C., et al. 2022. ACS Nano. 16: 16584-16597. PMID: 36001338
  13. Gold nanoclusters-loaded hydrogel formed by dimeric hydrogen bonds crosslinking: A novel strategy for multidrug-resistant bacteria-infected wound healing.  |  Ruan, Z., et al. 2022. Mater Today Bio. 16: 100426. PMID: 36133795
  14. Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors.  |  Chauvel, EN., et al. 1994. J Med Chem. 37: 1339-46. PMID: 7909847

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Mercaptohexanoic acid, 1 g

sc-239102
1 g
$280.00

Can I receive the product in Korea? Also do you have it in stock?

Asked by: GyuhanLee
Thank you for your question. https://www.scbt.com/resources/distributors KOREA For ordering or product information contact us at: Essence Medical Inc. 417 Leaders B/D, Yatapdong 342-1 Bundanggu Seongnam Gyeonggi-do Korea Phone: 82-31-707-1544 Fax: 82-31-707-1999 Email: info@essencemedical.com Website: www.essencemedical.com Koram Biotech Corporation 6F, Koram Venture Building 907-1 Daechi-Dong Kang Nam-Ku Seoul 135-080 Korea Phone: 82 (2) 556-0311 Fax: 82 (2) 556-0828 Email: koram@korambiotech.com Website: www.korambiotech.com
Answered by: Ling Chen
Date published: 2024-06-24

What is the purity of the product and shipping charges to Israel?

Asked by: Anna313
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot. For a quote with shipping charges to Israel, please call our European Support office toll-free at 00800 4573 8000, email europe@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2017-08-15
  • y_2026, m_4, d_29, h_11CST
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Rated 5 out of 5 by from Various publications cite the use of 6Various publications cite the use of 6-Mercaptohexanoic acid in the preparation of functionalized gold nanoparticles and hydrophilic self-assembled monolayers (SAMs) associated with gold substrates. -SCBT Publication Review
Date published: 2015-04-18
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6-Mercaptohexanoic acid is rated 5.0 out of 5 by 1.
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