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6-keto Prostaglandin F1α-d4 (CAS 82414-64-0)

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Alternate Names:
6-oxo-9α,11α,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
CAS Number:
82414-64-0
Purity:
≥99% deuterated forms (d1-d4)
Molecular Weight:
374.50
Molecular Formula:
C20H30D4O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-keto Prostaglandin F1α-d4 (6-keto PGF1α-d4) contains four deuterium atoms at positions 3, 3′, 4, and 4′. It is used as an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry.6-keto prostaglandin F1α (6-keto PGF1α) is the inactive, non-enzymatic hydrolysis product of PGI2(1,2). 6-keto PGF1α is a useful marker of PGI2 biosynthesis in vivo(3). When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1α(3).


6-keto Prostaglandin F1α-d4 (CAS 82414-64-0) References

1 Pace-Asciak, C.R. Isolation, structure, and biosynthesis of 6-ketoprostaglandin F1α in the rat stomach. J Am Chem Soc 98 2348-2349 (1976). 2 Johnson, R.A., Morton, D.R., Kinner, J.H., et al. The chemical structure of prostaglandin X (prostacyclin). Prostaglandins 12 915-928 (1976). 3 Brash, A.R., Jackson, E.K., Saggese, C.A., et al. Metabolic disposition of prostacyclin in humans. J Pharmacol Exp Ther 226 78-87 (1983).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-keto Prostaglandin F1α-d4, 25 µg

sc-221103
25 µg
$98.00

6-keto Prostaglandin F1α-d4, 50 µg

sc-221103A
50 µg
$186.00