Molecular structure of 6-Keto-prostaglandin F1α, CAS Number: 58962-34-8
6-Keto-prostaglandin F1α (CAS 58962-34-8)
See product citations (1)
Alternate Names:
6-oxo-9α,11α,15S-trihydroxy-prost-13E-en-1-oic acid; 6-Oxo-PGF1alpha; 6-Keto-PGF1alpha; 6-keto-prostaglandin F1a
Application:
6-Keto-prostaglandin F1α is a PGI 2 hydrolysis product used as a marker for PGI 2
CAS Number:
58962-34-8
Purity:
≥98%
Molecular Weight:
370.48
Molecular Formula:
C20H34O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
6-Keto-prostaglandin F1α (6-keto PGF1α) is the non-enzymatic hydrolysis product of prostacyclin (PGI2; sc-201231), and has therefore been used to measure the production of PGI2. Multiple tautomers of 6-Keto-prostaglandin F1α exist - at least one keto-form and two lactol-forms. Research has suggested that 6-Keto-prostaglandin F1α might counteract the action of prostacyclin.
6-Keto-prostaglandin F,[object Object], (CAS 58962-34-8) References
- The chemical structure of prostaglandin X (prostacyclin). | Whittaker, N., et al. 1976. Prostaglandins. 12: 915-28. PMID: 12538
- Maprotiline Ameliorates High Glucose-Induced Dysfunction in Renal Glomerular Endothelial Cells. | Zhou, Z. and Liu, S. 2022. Exp Clin Endocrinol Diabetes. 130: 596-603. PMID: 35320846
- Study on the antithrombotic effect and physiological mechanism of okanin. | Liu, Y., et al. 2022. Biomed Pharmacother. 153: 113358. PMID: 35785699
- Anti-atherosclerotic Effects of Myrtenal in High-Fat Diet-Induced Atherosclerosis in Rats. | Yu, L., et al. 2022. Appl Biochem Biotechnol. 194: 5717-5733. PMID: 35804285
- Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. | Vinokurtseva, A., et al. 2022. Exp Eye Res. 225: 109284. PMID: 36273575
- The protective effect of rivaroxaban with or without aspirin on inflammation, oxidative stress, and platelet reactivity in isoproterenol-induced cardiac injury in rats. | Abedalqader, NN., et al. 2023. Naunyn Schmiedebergs Arch Pharmacol. 396: 337-351. PMID: 36334131
- Potential prognostic markers of retained placenta in dairy cows identified by plasma metabolomics coupled with clinical laboratory indicators. | Li, Y., et al. 2022. Vet Q. 42: 199-212. PMID: 36369933
- Investigation of the hemostatic mechanism of Gardeniae fructus Praeparatus based on pharmacological evaluation and network pharmacology. | Zheng, Y., et al. 2022. Ann Transl Med. 10: 1093. PMID: 36388796
- Effect of omega-3 polyunsaturated fatty acid supplementation on oxidative stress parameters and sex hormone levels of modern genotype sows. | Roszkos, R., et al. 2023. Vet Med Sci. 9: 191-202. PMID: 36508581
- Metabolic disposition of prostacyclin in humans. | Brash, AR., et al. 1983. J Pharmacol Exp Ther. 226: 78-87. PMID: 6345756
- Changes of mean arterial pressure of the rat resulting from intracerebroventricular injections of prostacyclin or 6-keto-prostaglandin F1 alpha. | Kenney, NJ. 1983. Prostaglandins. 25: 335-42. PMID: 6346396
- Identification of the major metabolite of prostacyclin and 6-ketoprostaglandin F1 alpha in man. | Rosenkranz, B., et al. 1980. Biochim Biophys Acta. 619: 207-13. PMID: 6996737
- Mechanistic studies on the biosynthesis of 6-ketoprostaglandin F1alpha. | Pace-Asciak, CR. and Nashat, M. 1977. Biochim Biophys Acta. 487: 495-507. PMID: 884125
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Keto-prostaglandin F1α, 1 mg | sc-201238 | 1 mg | $159.00 | |||
6-Keto-prostaglandin F1α, 10 mg | sc-201238A | 10 mg | $816.00 |