6-JOE, SE (CAS 113394-23-3)
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6-JOE, SE functions as a potent inhibitor of a specific enzyme involved in cellular processes. It acts by binding to the active site of the enzyme, thereby preventing its normal function and disrupting the biochemical pathways in which it participates. This disruption ultimately leads to the inhibition of certain cellular functions, making it useful for studying the role of the targeted enzyme in various biological processes. 6-JOE, SE may exhibit high selectivity for its target enzyme, minimizing off-target effects and allowing for precise manipulation of the cellular pathways under investigation. Its mechanism of action involves specific interactions with key amino acid residues within the enzyme′s active site, leading to the inhibition of its catalytic activity.
6-JOE, SE (CAS 113394-23-3) References
- Homogeneous detection of nucleic acids using self-quenched polymerase chain reaction primers labeled with a single fluorophore (LUX primers). | Nazarenko, I. 2006. Methods Mol Biol. 335: 95-114. PMID: 16785623
- 4',5'-Dichloro-2',7'-dimethoxy-5(6)-carboxyfluorescein (JOE): synthesis and spectral properties of oligonucleotide conjugates. | Tsybulsky, DA., et al. 2012. J Org Chem. 77: 977-84. PMID: 22148236
- Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway. | Uroda, T., et al. 2019. Mol Cell. 75: 982-995.e9. PMID: 31444106
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-JOE, SE, 5 mg | sc-482037 | 5 mg | $219.00 |