Molecular structure of 6-Hydroxydopa, CAS Number: 23358-64-7
6-Hydroxydopa (CAS 23358-64-7)
Alternate Names:
2,4,5-Trihydroxy-DL-phenylalanine; 2,5-Dihydroxy-DL-tyrosine
Application:
6-Hydroxydopa is a precursor of the neurotoxin 6-hydroxydopamine; used to study parkinson′s
CAS Number:
23358-64-7
Molecular Weight:
213.19
Molecular Formula:
C9H11NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6-Hydroxydopa is the precursor of the catecholaminergic neurotoxin, 6-hydroxydopamine; converted to 6-hydroxydopamine by L-aromatic amino acid decarboxylase. Used in the study of Parkinson′s disease.
6-Hydroxydopa (CAS 23358-64-7) References
- The blood-brain barrier for catecholamines - revisited. | Kostrzewa, RM. 2007. Neurotox Res. 11: 261-71. PMID: 17449463
- Perinatal Lesioning and Lifelong Effects of the Noradrenergic Neurotoxin 6-Hydroxydopa. | Kostrzewa, RM. 2016. Curr Top Behav Neurosci. 29: 43-50. PMID: 26660536
- Neuroteratology and Animal Modeling of Brain Disorders. | Archer, T. and Kostrzewa, RM. 2016. Curr Top Behav Neurosci. 29: 1-40. PMID: 26857462
- Improved GMP-compliant multi-dose production and quality control of 6-[18F]fluoro-L-DOPA. | Luurtsema, G., et al. 2017. EJNMMI Radiopharm Chem. 1: 7. PMID: 29564384
- Exosomes rich in Wnt5 improved circadian rhythm dysfunction via enhanced PPARγ activity in the 6-hydroxydopamine model of Parkinson's disease. | Li, Z., et al. 2023. Neurosci Lett. 802: 137139. PMID: 36813077
- The effects of glutathione and ascorbic acid on the oxidations of 6-hydroxydopa and 6-hydroxydopamine. | Nappi, AJ. and Vass, E. 1994. Biochim Biophys Acta. 1201: 498-504. PMID: 7803483
- Effects of systemic administration of 6-hydroxydopamine, 6-hydroxydopa and 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on tuberoinfundibular dopaminergic neurons in the rat. | Lin, JY., et al. 1993. Brain Res. 624: 126-30. PMID: 8252384
- Catecholamine uptake inhibitors elevate 6-hydroxydopamine in brain after administration of 6-hydroxydopa. | Evans, J. and Cohen, G. 1993. Eur J Pharmacol. 232: 241-5. PMID: 8467861
- The effects of hydroxyl radical attack on dopa, dopamine, 6-hydroxydopa, and 6-hydroxydopamine. | Nappi, AJ., et al. 1995. Pigment Cell Res. 8: 283-93. PMID: 8789736
- Destruction of catecholamine-containing neurons by 6-hydroxydopa, an endogenous amine oxidase cofactor. | Kostrzewa, RM. and Brus, R. 1998. Amino Acids. 14: 175-9. PMID: 9871458
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Hydroxydopa, 10 mg | sc-291364 | 10 mg | $240.00 | |||
6-Hydroxydopa, 50 mg | sc-291364A | 50 mg | $533.00 |