Molecular structure of 6-Hydroxy Etodolac
6-Hydroxy Etodolac (CAS 101901-06-8)
Alternate Names:
1,8-Diethyl-1,3,4,9-tetrahydro-6-hydroxypyrano[3,4-b]indole-1-acetic Acid; RAK 901
Application:
6-Hydroxy Etodolac is a metabolite of the NSAID Etodoiac.
CAS Number:
101901-06-8
Molecular Weight:
303.35
Molecular Formula:
C17H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6-Hydroxy Etodolac functions as an anti-inflammatory by suppressing the function of cyclooxygenase, an enzyme responsible for generating prostaglandins. Prostaglandins are molecules involved in the inflammatory process. By inhibiting cyclooxygenase, 6-Hydroxy Etodolac decreases prostaglandin production, ultimately leading to inflammation reduction. Furthermore, 6-Hydroxy Etodolac serves as an analgesic by impeding the activity of adenosine deaminase, an enzyme.
6-Hydroxy Etodolac (CAS 101901-06-8) References
- Etodolac in equine urine and serum: determination by high-performance liquid chromatography with ultraviolet detection, confirmation, and metabolite identification by atmospheric pressure ionization mass spectrometry. | Koupai-Abyazani, MR., et al. 1999. J Anal Toxicol. 23: 200-9. PMID: 10369330
- Separation and identification of etodolac and its urinary phase I metabolites using capillary electrochromatography and on-line capillary electrochromatography-electrospray ionisation mass spectrometry coupling. | Strickmann, DB., et al. 2000. J Chromatogr A. 887: 393-407. PMID: 10961329
- Capillary electrochromatography-electrospray ionization mass spectrometry for the qualitative investigation of the drug etodolac and its metabolites in biological samples. | Strickmann, DB. and Blaschke, G. 2000. J Chromatogr B Biomed Sci Appl. 748: 213-9. PMID: 11092600
- Isolation of an unknown metabolite of the non-steroidal anti-inflammatory drug etodolac and its identification as 5-hydroxy etodolac. | Strickmann, DB. and Blaschke, G. 2001. J Pharm Biomed Anal. 25: 977-84. PMID: 11377082
- Evaluation of the stereoselective metabolism of the chiral analgesic drug etodolac by high-performance liquid chromatography. | Becker-Scharfenkamp, U. and Blaschke, G. 1993. J Chromatogr. 621: 199-207. PMID: 8294542
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Hydroxy Etodolac, 1 mg | sc-391185 | 1 mg | $231.00 | |||
6-Hydroxy Etodolac, 2 mg | sc-391185A | 2 mg | $332.00 | |||
6-Hydroxy Etodolac, 5 mg | sc-391185B | 5 mg | $576.00 | |||
6-Hydroxy Etodolac, 10 mg | sc-391185C | 10 mg | $1122.00 | |||
6-Hydroxy Etodolac, 25 mg | sc-391185D | 25 mg | $1938.00 | |||
6-Hydroxy Etodolac, 50 mg | sc-391185E | 50 mg | $2652.00 |