Date published: 2026-2-5

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6-Fluoro-2-naphthoic acid (CAS 5043-01-6)

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CAS Number:
5043-01-6
Purity:
97%
Molecular Weight:
190.17
Molecular Formula:
C11H7FO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Fluoro-2-naphthoic acid functions as a building block in organic synthesis. It is used to introduce the 6-fluoro-2-naphthoic acid moiety into various molecules for the purpose of creating new chemical entities. The mechanism of action of 6-fluoro-2-naphthoic acid involves its ability to undergo chemical reactions, such as esterification, amidation, or Suzuki-Miyaura coupling, to form covalent bonds with other molecules. 6-Fluoro-2-Naphthoic Acid can participate in these reactions as a nucleophile or electrophile, depending on the specific pathway being pursued. In this way, 6-fluoro-2-naphthoic acid contributes to the diversification of chemical libraries and the generation of novel compounds for development purposes. Its role in these processes is to enable the creation of molecular diversity and the exploration of structure-activity relationships within chemical space.


6-Fluoro-2-naphthoic acid (CAS 5043-01-6) References

  1. Opioid activity of spinally selective analogues of N-naphthoyl-β-naltrexamine in HEK-293 cells and mice.  |  Le Naour, M., et al. 2012. J Med Chem. 55: 670-7. PMID: 22136373
  2. Investigating the interaction of sunset yellow aggregates and 6-fluoro-2-naphthoic acid: increasing probe molecule complexity.  |  Katz, JR. and Day, IJ. 2014. Magn Reson Chem. 52: 435-9. PMID: 24861207
  3. Influence of structural isomerism and fluorine atom substitution on the self-association of naphthoic acid.  |  Briffitt, R. and Day, IJ. 2015. J Phys Chem B. 119: 6703-10. PMID: 25973655
  4. Less Exploited GPCRs in Precision Medicine: Targets for Molecular Imaging and Theranostics.  |  Franco Machado, J., et al. 2018. Molecules. 24: PMID: 30583594

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Fluoro-2-naphthoic acid, 1 g

sc-233575
1 g
$107.00