Date published: 2026-4-25

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6-Chloropyridine-2-carboxylic acid (CAS 4684-94-0)

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Alternate Names:
6-Chloropicolinic acid
CAS Number:
4684-94-0
Molecular Weight:
157.55
Molecular Formula:
C6H4ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Chloropyridine-2-carboxylic acid functions as a building block in organic synthesis. It is used to introduce the 6-chloropyridine-2-carboxylic acid moiety into various molecules for the purpose of creating new compounds with specific properties. The mechanism of action of 6-Chloropyridine-2-carboxylic acid involves its ability to undergo chemical reactions, such as nucleophilic substitution, to form new carbon-carbon or carbon-heteroatom bonds. This allows for the modification of molecular structures and the creation of diverse chemical entities. In a research and development setting, 6-Chloropyridine-2-carboxylic acid is useful for the synthesis of complex organic molecules, enabling the exploration of new chemical entities with potential applications in various fields.


6-Chloropyridine-2-carboxylic acid (CAS 4684-94-0) References

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  2. Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis.  |  Parra, LLL., et al. 2018. J Nat Prod. 81: 188-202. PMID: 29297684
  3. Clopyralid degradation by AOPs enhanced with zero valent iron.  |  Barbosa Ferreira, M., et al. 2020. J Hazard Mater. 392: 122282. PMID: 32105951
  4. Scale-up of electrokinetic permeable reactive barriers for the removal of organochlorine herbicide from spiked soils.  |  Maldonado, S., et al. 2021. J Hazard Mater. 417: 126078. PMID: 33992923
  5. Model study on the aqueous-phase hydrodechlorination of clopyralid on noble metal catalysts  |  L. Teevs, K.-D. Vorlop, U. Prüße. 2011. Catalysis Communications. 14: 96-100.
  6. Ruthenium(II)–arene complexes with substituted picolinato ligands: Synthesis, structure, spectroscopic properties and antiproliferative activity  |  Ivanka Ivanović a, Katarina K. Jovanović b, Nevenka Gligorijević b, Siniša Radulović b, Vladimir B. Arion c, Khalil Salem A.M. Sheweshein d, Živoslav Lj. Tešić d, Sanja Grgurić-Šipka d. 2014. Journal of Organometallic Chemistry. 749: 343-349.
  7. ZVI – Reactive barriers for the remediation of soils polluted with clopyralid: Are they really Worth?  |  J. Vidal a, C. Saez b, P. Cañizares b, V. Navarro c, R. Salazar a, M.A. Rodrigo b. 2018. Chemical Engineering Journal. 350: 100-107.
  8. Pyridine-2-carboxylato chelated acylrhodium(III) organometallics: Spectroscopic, structural and theoretical studies  |  Anikul Islam a, Suman Mandal a, Samantha J. Carrington b, Indranil Chakraborty c, Swarup Chattopadhyay a. 2019. Polyhedron. 172: 15-21.
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  10. Crystallographic, spectroscopic, thermal, optical investigations and density functional theory calculations for novel Co(II) and Mn(II) complexes  |  Necmi Dege, Ömer Tamer, Mavişe Yaman, Adil Başoğlu, Davut Avcı & Yusuf Atalay. 2021. Applied Physics A. 127: 132.
  11. Experimental and theoretical approaches on structural, spectroscopic (FT-IR and UV-Vis), nonlinear optical, and molecular docking analyses for Zn (II) and Cu (II) complexes of 6-chloropyridine-2-carboxylic acid  |  Necmi Dege, Ömer Tamer, Merve Şimşek, Davut Avcı, Mavişe Yaman, Adil Başoğlu, Yusuf Atalay. 2022. Applied Organometallic Chemistry. 36.
  12. Base-induced Sommelet–Hauser rearrangement of N-(pyridinylmethyl) tetraalkylammonium salts  |  Eiji Tayama a, Goshu Shimizu b, Ryo Nakao a. 2022. Tetrahedron. 111.
  13. Recent progress in physical and mathematical modelling of electrochemically assisted soil remediation processes  |  J. Isidro 1, R. López-Vizcaíno 2, A. Yustres 2, C. Sáez 1, V. Navarro 2, M.A. Rodrigo 1. 2022. Current Opinion in Electrochemistry. 36.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Chloropyridine-2-carboxylic acid, 1 g

sc-254880
1 g
$46.00