Date published: 2025-11-3

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6-Chloropiperonal (CAS 15952-61-1)

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Alternate Names:
6-Chloro-benzo[1,3]dioxole-5-carbaldehyde
CAS Number:
15952-61-1
Purity:
≥98%
Molecular Weight:
184.58
Molecular Formula:
C8H5ClO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Chloropiperonal is extensively utilized in research centered on organic synthesis, particularly in the formation of fragrance compounds and chemical intermediates. This chemical serves as a versatile building block due to the presence of both aldehyde and chloro groups, which allow for varied chemical reactions including condensation and substitution. Research involving 6-Chloropiperonal often explores its use in synthesizing novel derivatives that can be applied in creating complex aromatic compounds. Additionally, this compound is studied for its role in the development of heterocyclic structures, which are significant in various industrial applications.


6-Chloropiperonal (CAS 15952-61-1) References

  1. Potent nonpeptide endothelin antagonists: synthesis and structure-activity relationships of pyrazole-5-carboxylic acids.  |  Zhang, J., et al. 2000. Bioorg Med Chem Lett. 10: 2575-8. PMID: 11086733
  2. Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.  |  Prado, S., et al. 2004. Bioorg Med Chem. 12: 3943-53. PMID: 15210161
  3. Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.  |  Alig, L., et al. 2008. J Med Chem. 51: 2115-27. PMID: 18335976
  4. Pd-catalyzed diastereoselective allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl)-α-methylene-γ-butyrolactones with a syn configuration.  |  Zhang, F., et al. 2013. Chem Commun (Camb). 49: 4697-9. PMID: 23589825
  5. The synthesis and characterisation of MDMA derived from a catalytic oxidation of material isolated from black pepper reveals potential route specific impurities.  |  Plummer, CM., et al. 2016. Sci Justice. 56: 223-230. PMID: 27162021
  6. Synthesis and cytotoxic activity of pyranophenanthridine analogues of fagaronine and acronycine.  |  Razafimbelo, J., et al. 1998. Chem Pharm Bull (Tokyo). 46: 34-41. PMID: 9468635
  7. Alkaloids from Crinum firmifolium var. hygrophilum  |  J Razafimbelo, M Andriantsiferana, G Baudouin. 1996. Phytochemistry. 41(1): 323-326.
  8. Chapter Three Recent Advances in the Total Synthesis of Amaryllidaceae Alkaloids  |  Prabhakar, S., & Tavares, M. R. 2001. Alkaloids: Chemical and Biological Perspectives. 15: 433-572.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Chloropiperonal, 2 g

sc-268260
2 g
$71.00