Date published: 2026-4-29

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6-Chlorohexanoic acid (CAS 4224-62-8)

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Alternate Names:
6-Chloro-N-Hexanoic Acid
CAS Number:
4224-62-8
Molecular Weight:
150.6
Molecular Formula:
C6H11ClO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Chlorohexanoic acid is a carboxylate used in fluorescence analysis, chromatography, and various activity tests. Shown to have antimicrobial properties against fungi and bacteria, as well as a high rate of stability in fruit extracts. This compound can be affixed to metal surfaces or electrodes coated with caproic acid, making it useful for electrochemical impedance spectroscopy research. 6-Chlorohexanoic Acid is used as a starting material in producing 2,6-Dichloro-N-(2,6-dimethylphenyl)hexanamide.


6-Chlorohexanoic acid (CAS 4224-62-8) References

  1. One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and chloroalkanes.  |  Zeng, K., et al. 2018. Chem Sci. 9: 446-456. PMID: 29629116
  2. Biodegradation of Endocrine-Disrupting Chemicals and Residual Organic Pollutants of Pulp and Paper Mill Effluent by Biostimulation.  |  Chandra, R., et al. 2018. Front Microbiol. 9: 960. PMID: 29867864
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  4. A robust and economical pulse-chase protocol to measure the turnover of HaloTag fusion proteins.  |  Merrill, RA., et al. 2019. J Biol Chem. 294: 16164-16171. PMID: 31511325
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  6. Tag-mediated single-step purification and immobilization of recombinant proteins toward protein-engineered advanced materials.  |  Freitas, AI., et al. 2022. J Adv Res. 36: 249-264. PMID: 35127175
  7. Preparation and characterization of immobilized 5-HT1A receptor stationary phase for high throughput screening of the receptor-binding ligands from complex systems like Curcuma wenyujin Y. H. Chen et C. Ling extract.  |  Chen, YY., et al. 2022. J Pharm Biomed Anal. 211: 114632. PMID: 35131672
  8. Identifying potential ligands specifically binding to beta1-adrenoceptor from Radix Aconiti Lateralis Praeparata extract by affinity chromatographic method.  |  Jin, Y., et al. 2022. J Pharm Biomed Anal. 220: 115022. PMID: 36063625
  9. A Strategy for Accessing Nanobody-Based Electrochemical Sensors for Analyte Detection in Complex Media.  |  Fan, R., et al. 2022. ECS Sens Plus. 1: PMID: 36338794
  10. Immobilization of M3 Muscarinic Receptor to Rapidly Analyze Drug-Protein Interactions and Bioactive Components in a Natural Plant.  |  Fan, H., et al. 2023. Int J Mol Sci. 24: PMID: 37108332
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  12. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents.  |  Struga, M., et al. 2023. ACS Omega. 8: 18663-18684. PMID: 37273589

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Chlorohexanoic acid, 1 g

sc-489775
1 g
$23.00