Date published: 2026-4-26

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6-Chloro-1-benzofuran-2-carboxylic Acid (CAS 442125-04-4)

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CAS Number:
442125-04-4
Molecular Weight:
196.59
Molecular Formula:
C9H5ClO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Chloro-1-benzofuran-2-carboxylic Acid is a compound that is of particular interest in organic chemistry and materials science research due to its heterocyclic core and functional groups. Its carboxylic acid moiety makes it a versatile precursor for the synthesis of various amide, ester, and anhydride derivatives, which can be valuable for further chemical transformations. The chlorine substituent on the benzofuran ring system presents opportunities for nucleophilic substitution reactions, potentially leading to a wide array of substituted benzofurans. Studies involving 6-Chloro-1-benzofuran-2-carboxylic Acid often focus on the development of new synthetic routes to harness the reactivity of the benzofuran moiety, which is a structure of interest due to its presence in natural products and potential optoelectronic applications. Additionally, this compound can be used in the design of ligands for metal coordination chemistry, where the aromatic system may contribute to the stability and electronic properties of the resulting metal complexes.


6-Chloro-1-benzofuran-2-carboxylic Acid (CAS 442125-04-4) References

  1. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.  |  Yoshikawa, K., et al. 2009. Bioorg Med Chem. 17: 8206-20. PMID: 19884015

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Chloro-1-benzofuran-2-carboxylic Acid, 250 mg

sc-505032
250 mg
$306.00