6-Aza-2-thiothymine (CAS 615-76-9)
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6-Aza-2-thiothymine is a heterocyclic compound that is of interest in the field of nucleic acid chemistry. It is an analog of thymine, one of the four nucleobases in the DNA molecule, with a nitrogen atom replacing a carbon in the ring structure and a sulfur atom substituting for an oxygen atom. This compound is primarily used in studies aimed at understanding the effects of such modifications on the structure, stability, and functionality of nucleic acids. Researchers employ 6-Aza-2-thiothymine to probe the specificity of DNA polymerases and other enzymes that interact with nucleic acids, as its altered hydrogen bonding pattern provides insights into enzyme-substrate recognition. Additionally, it is used in the design of novel oligonucleotides with potential applications in antisense technology and as probes for DNA-protein interactions. Its incorporation into DNA strands helps in studying the physicochemical properties of nucleic acids, including their duplex formation, thermal stability, and response to mutagenic agents.
6-Aza-2-thiothymine (CAS 615-76-9) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Aza-2-thiothymine, 5 g | sc-239089 | 5 g | $92.00 | |||
6-Aza-2-thiothymine, 25 g | sc-239089A | 25 g | $377.00 | |||
6-Aza-2-thiothymine, 100 g | sc-239089B | 100 g | $510.00 |