Molecular structure of 6-Amino-2-cyanobenzothiazole, CAS Number: 7724-12-1
6-Amino-2-cyanobenzothiazole (CAS 7724-12-1)
Alternate Names:
2-Cyano-6-aminobenzothiazole; 6-Amino-2-benzothiazolecarbonitrile
Application:
6-Amino-2-cyanobenzothiazole is a heterocyclic building block useful for synthesis
CAS Number:
7724-12-1
Purity:
≥95%
Molecular Weight:
175.21
Molecular Formula:
C8H5N3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
6-Amino-2-cyanobenzothiazole (6-AT) is utilized in processes that facilitate the creation of peptides, proteins, and enzymes. The compound operates by attaching to specific biological molecules, which can alter their typical activities, thus achieving the intended outcome. For instance, 6-Amino-2-cyanobenzothiazole is capable of binding to and inhibiting certain enzymes, leading to the suppression of specific biochemical pathways.
6-Amino-2-cyanobenzothiazole (CAS 7724-12-1) References
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- Aminoluciferins as functional bioluminogenic substrates of firefly luciferase. | Takakura, H., et al. 2011. Chem Asian J. 6: 1800-10. PMID: 21416616
- A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. | Godinat, A., et al. 2013. ACS Chem Biol. 8: 987-99. PMID: 23463944
- Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-triggered nanoaggregation probe. | Shen, B., et al. 2013. Angew Chem Int Ed Engl. 52: 10511-4. PMID: 23881906
- A biocompatible 'split luciferin' reaction and its application for non-invasive bioluminescent imaging of protease activity in living animals. | Godinat, A., et al. 2014. Curr Protoc Chem Biol. 6: 169-189. PMID: 25205565
- Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole. | Hauser, JR., et al. 2016. Beilstein J Org Chem. 12: 2019-2025. PMID: 27829906
- Synthesis of N-peptide-6-amino-D-luciferin Conjugates. | Kovács, AK., et al. 2018. Front Chem. 6: 120. PMID: 29725588
- Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay. | Keyser, SGL., et al. 2018. J Org Chem. 83: 7467-7479. PMID: 29771122
- Bioorthogonal chemistry in bioluminescence imaging. | Godinat, A., et al. 2018. Drug Discov Today. 23: 1584-1590. PMID: 29778694
- N, S-Double Labeling of N-Terminal Cysteines via an Alternative Conjugation Pathway with 2-Cyanobenzothiazole. | Wang, W. and Gao, J. 2020. J Org Chem. 85: 1756-1763. PMID: 31880156
- Recent applications of CBT-Cys click reaction in biological systems. | Zhu, Y., et al. 2022. Bioorg Med Chem. 68: 116881. PMID: 35716587
- An Efficient, Site-Selective and Spontaneous Peptide Macrocyclisation During in vitro Translation. | Liu, M., et al. 2023. Chemistry. 29: e202203923. PMID: 36529683
- Synthesis and characterization of a bioluminogenic substrate for alpha-chymotrypsin. | Monsees, T., et al. 1994. Anal Biochem. 221: 329-34. PMID: 7810874
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
6-Amino-2-cyanobenzothiazole, 100 mg | sc-233526 | 100 mg | $256.00 | |||
6-Amino-2-cyanobenzothiazole, 1 g | sc-233526A | 1 g | $1656.00 | |||
6-Amino-2-cyanobenzothiazole, 5 g | sc-233526B | 5 g | $5806.00 | |||
6-Amino-2-cyanobenzothiazole, 10 g | sc-233526C | 10 g | $11806.00 | |||
6-Amino-2-cyanobenzothiazole, 25 g | sc-233526D | 25 g | $21606.00 |