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5′-O-Benzoyl-2,3′-anhydrothymidine (CAS 70838-44-7)

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Application:
5′-O-Benzoyl-2,3′-anhydrothymidine is an intermediate in the preparation of anti-HIV pharmaceuticals
CAS Number:
70838-44-7
Molecular Weight:
328.32
Molecular Formula:
C17H16N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5′-O-Benzoyl-2,3′-anhydrothymidine is an intermediate in the preparation of anti-HIV pharmaceuticals.


5′-O-Benzoyl-2,3′-anhydrothymidine (CAS 70838-44-7) References

  1. Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: 'nitric oxide donor' agents for evaluation as anticancer and antiviral agents.  |  Naimi, E., et al. 2003. J Med Chem. 46: 995-1004. PMID: 12620076
  2. Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel.  |  Hsu, AR., et al. 2007. J Nucl Med. 48: 445-54. PMID: 17332623
  3. Comparative evaluation of F-18 FDOPA, F-18 FDG, and F-18 FLT-PET/CT for metabolic imaging of low grade gliomas.  |  Tripathi, M., et al. 2009. Clin Nucl Med. 34: 878-83. PMID: 20139821
  4. Levels of human equilibrative nucleoside transporter-1 are higher in proliferating regions of A549 tumor cells grown as tumor xenografts in vivo.  |  Plotnik, DA., et al. 2012. Nucl Med Biol. 39: 1161-6. PMID: 22985987
  5. Synthesis, Conformation of 3′-(Tetrazole-2 ″-yl)-3′-deoxythymidine and its 5 ″-Derivatives. Substrate Properties of 3′-(Tetrazole-2 ″-yl)-3′-deoxythymidine 5′-Triphosphate  |  Ostrovskii, V. A., Studentsov, E. P., Poplavskii, V. S., Ivanova, N. V., Gurskaya, G. V., Zavodnik, V. E.,.. & Krayevsky, A. A. 1995. Nucleosides, Nucleotides & Nucleic Acids. 14(6): 1289-1300.
  6. Mechanisms of 5'-O-Benzoyl-2, 3'-anhydrothymidine Reactions with Nucleophiles: II. Kinetics of the Reaction with Triethylammonium Tetrazolide in DMF  |  Malin, A. A., Korchevskaya, E. V., Shcherbinin, M. B., & Ostrovskii, V. A. 2001. Russian Journal of Organic Chemistry. 37: 1767-1770.
  7. Synthesis of novel thymidine derivatives containing a polycyclic tetrazole linker  |  Filichev, V. V., Jasko, M. V., Malin, A. A., Zubarev, V. Y., & Ostrovskii, V. A. 2002. Tetrahedron letters. 43(10): 1901-1903.
  8. Simplified, automated synthesis of 3′[18F] fluoro-3′-deoxy-thymidine ([18F] FLT) and simple method for metabolite analysis in plasma  |  Reischl, G., Blocher, A., Wei, R., Ehrlichmann, W., Kuntzsch, M., Solbach, C.,.. & Machulla, H. J. 2006. Radiochimica Acta. 94(8): 447-451.
  9. Kinetics and mechanism of 5-vinyltetrazole alkylation  |  Pavlyukova, Y. N., Trifonov, R. E., Yugai, E. V., Aleshunin, P. A., Tselinskii, I. V., & Ostrovskii, V. A. 2008. Russian Journal of Organic Chemistry. 44: 1711-1715.
  10. Synthesis and functionalization of 5‐substituted tetrazoles  |  Roh, J., Vávrová, K., & Hrabálek, A. 2012. European Journal of Organic Chemistry. 31: 6101-6118.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5'-O-Benzoyl-2,3'-anhydrothymidine, 100 mg

sc-221062
100 mg
$320.00