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5′-(N-Cyclopropyl)carboxamidoadenosine (CAS 50908-62-8)

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Alternate Names:
CPCA
Application:
5′-(N-Cyclopropyl)carboxamidoadenosine is an activator of Adenosine A Receptor
CAS Number:
50908-62-8
Molecular Weight:
320.30
Molecular Formula:
C13H16N6O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5′-(N-Cyclopropyl)carboxamidoadenosine is an activator of Adenosine A Receptor.


5′-(N-Cyclopropyl)carboxamidoadenosine (CAS 50908-62-8) References

  1. Mechanism of decreased adenosine protection in reperfusion injury of aging rats.  |  Gao, F., et al. 2000. Am J Physiol Heart Circ Physiol. 279: H329-38. PMID: 10899073
  2. Modification of cardiovascular response of adenosine A2 receptor agonist by adenylate cyclase in the spinal cord of rats.  |  Koh, HC., et al. 2000. Neurosci Lett. 293: 45-8. PMID: 11065134
  3. The effect of adenosine on blood pressure variability in sinoaortic denervated rats is mediated by adenosine A2a-Receptor.  |  Shen, FM. and Su, DF. 2000. J Cardiovasc Pharmacol. 36: 681-6. PMID: 11065230
  4. Erythroid carbonic anhydrase and hsp70 expression in chick embryonic development: role of cAMP and hypoxia.  |  Dragon, S. and Baumann, R. 2001. Am J Physiol Regul Integr Comp Physiol. 280: R870-8. PMID: 11171668
  5. Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle.  |  Gopalakrishnan, SM., et al. 2002. J Pharmacol Exp Ther. 300: 910-7. PMID: 11861797
  6. ATP-sensitive potassium channels are involved in adenosine-induced reduction of blood pressure variability in spontaneously hypertensive rats.  |  Shen, FM., et al. 2004. J Cardiovasc Pharmacol. 44: 87-92. PMID: 15175562
  7. Coupling of the human A1 adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation.  |  Cordeaux, Y., et al. 2004. Br J Pharmacol. 143: 705-14. PMID: 15302686
  8. Hydrogen sulphide in the hypothalamus causes an ATP-sensitive K+ channel-dependent decrease in blood pressure in freely moving rats.  |  Dawe, GS., et al. 2008. Neuroscience. 152: 169-77. PMID: 18201837
  9. Synthesis, characterization and biological evaluation of C5'-N-cyclopropylcarboxamido-C6-amino-C2-alkynylated purine nucleoside analogues.  |  Ananda Mohan, A., et al. 2017. Nucleosides Nucleotides Nucleic Acids. 36: 637-651. PMID: 29185853
  10. CD73 contributes to anti-inflammatory properties of afferent lymphatic endothelial cells in humans and mice.  |  Eichin, D., et al. 2021. Eur J Immunol. 51: 231-246. PMID: 32970335
  11. Effects of several 5'-carboxamide derivatives of adenosine on adenosine receptors of human platelets and rat fat cells.  |  Ukena, D., et al. 1984. Naunyn Schmiedebergs Arch Pharmacol. 327: 36-42. PMID: 6092968
  12. Nitric oxide participates in the hypotensive effect induced by adenosine A2 subtype receptor stimulation.  |  Stella, L., et al. 1995. J Cardiovasc Pharmacol. 25: 1001-5. PMID: 7564326
  13. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats.  |  Malhotra, J. and Gupta, YK. 1997. Br J Pharmacol. 120: 282-8. PMID: 9117121
  14. Induction of aromatase activity in human adipose tissue stromal cells by extracellular nucleotides--evidence for P2-purinoceptors in adipose tissue.  |  Schmidt, M. and Löffler, G. 1998. Eur J Biochem. 252: 147-54. PMID: 9523724
  15. Adenosine 3':5'-cyclic monophosphate (cAMP)-inducible pyrimidine 5'-nucleotidase and pyrimidine nucleotide metabolism of chick embryonic erythrocytes.  |  Dragon, S., et al. 1998. Blood. 91: 3052-8. PMID: 9531619

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5′-(N-Cyclopropyl)carboxamidoadenosine, 25 mg

sc-221052
25 mg
$150.00