Date published: 2026-4-24

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5β-Cholanic acid-3α,6β,7α-triol (CAS 2393-58-0)

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Alternate Names:
α-Muricholic acid; 5β-Cholanic Acid-3α,6β,7α-triol; 3α,6β,7α-Trihydroxy-5β-cholan-24-oic Acid; 3α,6β,7α-Trihydroxy-5β-cholanic Acid
Application:
5β-Cholanic acid-3α,6β,7α-triol is 5β-Cholanic acid-3α,6β,7α-triol is a cholesterol used for proteomics research.
CAS Number:
2393-58-0
Molecular Weight:
408.57
Molecular Formula:
C24H40O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5β-Cholanic acid-3α,6β,7α-triol is a cholesterol used for proteomics research. It is a murine-specific primary bile acid. It has roles in various biological processes, particularly in the digestion and absorption of fats and fat-soluble vitamins in the intestinal tract. Its interaction with lipids can be studied to understand the mechanisms of lipid solubilization and transport. In environmental science, the biodegradability and natural occurrence of compounds like 5β-Cholanic acid-3α,6β,7α-triol can be explored to assess their impact on ecosystems, particularly in water bodies where bile acids from animal waste might accumulate.


5β-Cholanic acid-3α,6β,7α-triol (CAS 2393-58-0) References

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  2. Bile acid analysis in various biological samples using ultra performance liquid chromatography/electrospray ionization-mass spectrometry (UPLC/ESI-MS).  |  Hagio, M., et al. 2011. Methods Mol Biol. 708: 119-29. PMID: 21207286
  3. Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method.  |  García-Cañaveras, JC., et al. 2012. J Lipid Res. 53: 2231-2241. PMID: 22822028
  4. Simultaneous and rapid analysis of bile acids including conjugates by supercritical fluid chromatography coupled to tandem mass spectrometry.  |  Taguchi, K., et al. 2013. J Chromatogr A. 1299: 103-9. PMID: 23768533
  5. Early Increases in Bile Acids Post Roux-en-Y Gastric Bypass Are Driven by Insulin-Sensitizing, Secondary Bile Acids.  |  Albaugh, VL., et al. 2015. J Clin Endocrinol Metab. 100: E1225-33. PMID: 26196952
  6. Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.  |  Flynn, CR., et al. 2015. Nat Commun. 6: 7715. PMID: 26197299
  7. High-fat Diet-induced Intestinal Hyperpermeability is Associated with Increased Bile Acids in the Large Intestine of Mice.  |  Murakami, Y., et al. 2016. J Food Sci. 81: H216-22. PMID: 26595891
  8. Combination of soya pulp and Bacillus coagulans lilac-01 improves intestinal bile acid metabolism without impairing the effects of prebiotics in rats fed a cholic acid-supplemented diet.  |  Lee, Y., et al. 2016. Br J Nutr. 116: 603-10. PMID: 27464459
  9. Ingestion of difructose anhydride III partially suppresses the deconjugation and 7α-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet.  |  Lee, DG., et al. 2019. Biosci Biotechnol Biochem. 83: 1329-1335. PMID: 30912732
  10. Association between 12α-hydroxylated bile acids and hepatic steatosis in rats fed a high-fat diet.  |  Hori, S., et al. 2020. J Nutr Biochem. 83: 108412. PMID: 32534424
  11. Primary 12α-Hydroxylated Bile Acids Lower Hepatic Iron Concentration in Rats.  |  Hori, S., et al. 2021. J Nutr. 151: 523-530. PMID: 33438034
  12. Dietary raffinose ameliorates hepatic lipid accumulation induced by cholic acid via modulation of enterohepatic bile acid circulation in rats.  |  Maegawa, K., et al. 2022. Br J Nutr. 127: 1621-1630. PMID: 34256877
  13. The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.  |  Blake, SJ., et al. 2021. Cell Rep Med. 2: 100464. PMID: 35028606

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5β-Cholanic acid-3α,6β,7α-triol, 5 mg

sc-396734
5 mg
$367.00