Date published: 2026-2-2

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5α-Cholestan-3β-ol (CAS 80-97-7)

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Alternate Names:
β-Cholestanol
Application:
5α-Cholestan-3β-ol is a derivitized steroid compound
CAS Number:
80-97-7
Molecular Weight:
388.67
Molecular Formula:
C27H48O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5α-Cholestan-3β-ol, a naturally occurring sterol, has been extensively studied in various scientific research applications due to its unique chemical structure and properties. Researchers have employed this compound to investigate its role in biological systems, including its effects on cell signaling pathways, membrane structure, and lipid metabolism. Specifically, studies have shown that 5α-Cholestan-3β-ol can modulate the activity of key proteins involved in cell signaling, such as protein kinase C and G-protein coupled receptors. Additionally, this compound has been used as a model system to study the mechanisms of lipid raft formation and dynamics, which are critical for cellular processes such as cell adhesion, migration, and apoptosis. Furthermore, 5α-Cholestan-3β-ol has been used in the study of plant biology, enabling researchers to investigate the genetic regulation of sterol biosynthesis and the development of novel crop varieties with improved sterol content. The unique properties of 5α-Cholestan-3β-ol have also made it an attractive component in the development of novel nanomaterials and bioactive compounds, with potential applications in biotechnology and materials science. Overall, the scientific research applications of 5α-Cholestan-3β-ol have contributed significantly to our understanding of lipid biology, cell signaling, and plant biology.


5α-Cholestan-3β-ol (CAS 80-97-7) References

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  2. 5alpha Cholestan-3beta-ol: its distribution in tissues and its synthesis from cholesterol in the guinea pig.  |  WERBIN, H., et al. 1962. J Biol Chem. 237: 2072-7. PMID: 14006176
  3. Sterol stringency of proliferation and cell cycle progression in human cells.  |  Suárez, Y., et al. 2005. Biochim Biophys Acta. 1734: 203-13. PMID: 15904877
  4. Evaluation of potential sewage contamination by fecal sterol biomarkers adsorbed in natural biofilms.  |  Froehner, S. and Sánez, J. 2013. Environ Sci Process Impacts. 15: 2080-6. PMID: 24064988
  5. Discrimination of Stereoisomers by Their Enantioselective Interactions with Chiral Cholesterol-Containing Membranes.  |  Tsuchiya, H. and Mizogami, M. 2017. Molecules. 23: PMID: 29295605
  6. Development of Improved Synthetic Routes to Pixatimod (PG545), a Sulfated Oligosaccharide-Steroid Conjugate.  |  Chhabra, M., et al. 2021. Bioconjug Chem. 32: 2420-2431. PMID: 34652896
  7. Fossil Biomarkers and Biosignatures Preserved in Coprolites Reveal Carnivorous Diets in the Carboniferous Mazon Creek Ecosystem.  |  Tripp, M., et al. 2022. Biology (Basel). 11: PMID: 36138768
  8. The oxidation of steroid derivatives by the CYP125A6 and CYP125A7 enzymes from Mycobacterium marinum.  |  Ghith, A. and Bell, SG. 2023. J Steroid Biochem Mol Biol. 235: 106406. PMID: 37793577
  9. Biosynthesis of cholestanol: 5-alpha-cholestan-3-one reductase of rat liver.  |  Shefer, S., et al. 1966. J Lipid Res. 7: 763-71. PMID: 4381999
  10. Some enzymatic properties of 3beta-hydroxysteroid oxidase produced by Streptomyces violascens.  |  Tomioka, H., et al. 1976. J Biochem. 79: 903-15. PMID: 956143

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5α-Cholestan-3β-ol, 10 g

sc-214347
10 g
$89.00

5α-Cholestan-3β-ol, 25 g

sc-214347A
25 g
$161.00