5(Z),8(Z),11(Z),14(Z),17(Z),20(Z)-Tricosahexaenoic acid (CAS 1095558-71-6)

5(Z),8(Z),11(Z),14(Z),17(Z),20(Z)-Tricosahexaenoic acid, commonly known as tricosahexaenoic acid (THA), is a long-chain polyunsaturated fatty acid that has been widely investigated in scientific research, particularly in the fields of nutrition, lipid metabolism, and cellular signaling. THA belongs to the omega-3 fatty acid family and exhibits unique biological properties. Mechanistically, THA exerts its effects through various pathways, including lipid-mediated signaling, gene expression modulation, and cellular function regulation. Research has focused on elucidating the impact of THA on brain health and cognitive function, as it is an essential component of neuronal membranes and contributes to synaptic plasticity, neurotransmission, and neuroprotection. THA has also been studied in the context of cardiovascular health, as it shows potential in reducing inflammation, improving lipid profiles, and modulating vascular function. Moreover, THA′s involvement in immunomodulation and its influence on inflammatory pathways have been investigated. Experimental models, ranging from cell cultures to animal models, have been employed to explore the specific mechanisms of action and biological effects of THA. By deepening our understanding of THA′s functions, scientific research contributes to unraveling the physiological significance of this fatty acid and its potential implications for human health. The versatile nature of THA makes it a subject of ongoing investigation in diverse areas, including nutrition, neuroscience, and cardiovascular research.