Molecular structure of 5-trans Fluprostenol, CAS Number: 57968-83-9
5-trans Fluprostenol (CAS 57968-83-9)
Application:
5-trans Fluprostenol is a fluprostenol impurity
CAS Number:
57968-83-9
Molecular Weight:
458.5
Molecular Formula:
C23H29F3O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.1 Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol.2 5-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date.
5-trans Fluprostenol (CAS 57968-83-9) References
- Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. | Hellberg, MR., et al. 2001. J Ocul Pharmacol Ther. 17: 421-32. PMID: 11765147
- Non-targeted Metabolomics Analysis Reveals Distinct Metabolic Profiles Between Positive and Negative Emotional Tears of Humans: A Preliminary Study. | Liang, H., et al. 2023. Cureus. 15: e42985. PMID: 37671209
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-trans Fluprostenol, 1 mg | sc-205140 | 1 mg | $140.00 | |||
5-trans Fluprostenol, 5 mg | sc-205140A | 5 mg | $630.00 |