Molecular structure of 5(S)-HpEPE, CAS Number: 143292-98-2
5(S)-HpEPE (CAS 143292-98-2)
Alternate Names:
5S-hydroperoxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid
Application:
5(S)-HpEPE is a peroxidase substrate
CAS Number:
143292-98-2
Molecular Weight:
334.45
Molecular Formula:
C20H30O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA. 5(S)-HpEPE is metabolized to LTA5, a key intermediate in formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.
5(S)-HpEPE (CAS 143292-98-2) References
- Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. | Kulkarni, PS., et al. 1987. J Ocul Pharmacol. 3: 349-56. PMID: 2846724
- Structural basis for altered positional specificity of 15-lipoxygenase-1 with 5S-HETE and 7S-HDHA and the implications for the biosynthesis of resolvin E4. | Perry, SC., et al. 2022. Arch Biochem Biophys. 727: 109317. PMID: 35709965
- Characterization of Arachidonate 5S-Lipoxygenase from Danio rerio with High Activity for the Production of 5S- and 7S-Hydroxy Polyunsaturated Fatty Acids. | Shin, KC., et al. 2023. Appl Biochem Biotechnol. 195: 958-972. PMID: 36251113
- Biological Roles of 5-Oxo-6,8,11,14-Eicosatetraenoic Acid and the OXE Receptor in Allergic Diseases: Collegium Internationale Allergologicum Update 2024. | Lin, L., et al. 2024. Int Arch Allergy Immunol. 185: 301-310. PMID: 38176394
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5(S)-HpEPE, 25 µg | sc-221074 | 25 µg | $114.00 | |||
5(S)-HpEPE, 50 µg | sc-221074A | 50 µg | $218.00 |