5(S),12(S)-DiHETE (CAS 73151-67-4)
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5(S),12(S)-DiHETE is a compound that acts as a potent eicosanoid lipid mediator. Leukotrienes comprise a family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors. 5(S),12(S)-DiHETE (6-trans-12-epi-LTB4) is synthesized via nonenzymatic hydrolysis of LTA4 (sc-201039) and by myeloperoxidase-dependent metabolism of cysteinyl leukotrienes. See 5-Lipoxygenase Pathway for structure
5(S),12(S)-DiHETE (CAS 73151-67-4) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5(S),12(S)-DiHETE, 25 µg | sc-200426 | 25 µg | $446.00 | |||
5(S),12(S)-DiHETE, 50 µg | sc-200426A | 50 µg | $772.00 |