5-Pyrimidinemethanamine (CAS 25198-95-2)
QUICK LINKS
5-Pyrimidinemethanamine (5-PM) is a pyrimidine compound that may be useful in nucleotide analog studies and as a potential synthetic intermediate. It acts as a nucleophile, reacting with electrophiles in the presence of an acid catalyst. The reaction proceeds through a two-step mechanism, in which the pyrimidine reacts with formaldehyde to form an intermediate, which then undergoes a rearrangement to form 5-Pyrimidinemethanamine. Its structure makes it a versatile building block for synthesizing more complex molecules, particularly in agrochemical research. The presence of both a pyrimidine ring and an amine group offers multiple sites for chemical modification or interaction. Given its resemblance to naturally occurring pyrimidine bases in DNA (like cytosine and thymine), derivatives of 5-PM might be studied for their interactions with biological systems or as analogs in biochemical research.
5-Pyrimidinemethanamine (CAS 25198-95-2) References
- The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. | Deaton, DN., et al. 2019. Bioorg Med Chem. 27: 1456-1478. PMID: 30858025
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-Pyrimidinemethanamine, 100 mg | sc-210380 | 100 mg | $224.00 |