Molecular structure of 5-(p-Methylphenyl)-5-phenylhydantoin, CAS Number: 51169-17-6
5-(p-Methylphenyl)-5-phenylhydantoin (CAS 51169-17-6)
Alternate Names:
5-(4-Methylphenyl)-5-phenyl-2,4-imidazolidinedione; 5-(4′-Methylphenyl)-5-phenylhydantoin; 5-Phenyl-5-(4-tolyl)hydantoin
Application:
5-(p-Methylphenyl)-5-phenylhydantoin is An antibody agent
CAS Number:
51169-17-6
Molecular Weight:
266.29
Molecular Formula:
C16H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-(p-Methylphenyl)-5-phenylhydantoin, also known as 5-MPH, is a synthetic compound extensively utilized in various scientific research endeavors. This compound belongs to the hydantoin family, which comprises derivatives of hydantoin—a heterocyclic compound featuring a five-membered ring containing oxygen and nitrogen atoms. It is believed that the primary mode of action of 5-(p-Methylphenyl)-5-phenylhydantoin involves its role as an agonist at the gamma-aminobutyric acid (GABA) receptors. Additionally, there have been suggestions that this compound may act as an antagonist at the N-methyl-d-aspartate (NMDA) receptors.
5-(p-Methylphenyl)-5-phenylhydantoin (CAS 51169-17-6) References
- Thin-layer chromatographic determination of barbiturates and phenytoin in serum and blood. | Breyer, U. and Villumsen, D. 1975. J Chromatogr. 115: 493-500. PMID: 1206061
- Molecularly imprinted polymers for simultaneous determination of antiepileptics in river water samples by liquid chromatography-tandem mass spectrometry. | Hoshina, K., et al. 2009. J Chromatogr A. 1216: 4957-62. PMID: 19439306
- Direct serum injection high-performance liquid chromatographic method for the simultaneous determination of phenobarbital, carbamazepine and phenytoin. | Rainbow, SJ., et al. 1990. J Chromatogr. 527: 389-96. PMID: 2201693
- A quantitative phenytoin GC-MS method and its validation for samples from human ex situ brain microdialysis, blood and saliva using solid-phase extraction. | Hösli, R., et al. 2013. J Anal Toxicol. 37: 102-9. PMID: 23325763
- Development of a useful single-reference HPLC method for therapeutic drug monitoring of phenytoin and carbamazepine in human plasma. | Sakaguchi, Y., et al. 2023. Anal Sci. 39: 447-454. PMID: 36637705
- Simultaneous assay of diazepam, chlordiazepoxide, N-desmethyldiazepam, N-desmethylchloridazepoxide, and demoxepam in serum by high performance, liquid chromatography. | Foreman, JM., et al. 1980. Clin Biochem. 13: 122-5. PMID: 6774834
- Micro-scale anticonvulsant assay with use of nitrogen/phosphorus detector and on-column methylation compared with a macro-scale procedure involving flame-ionization detection. | Least, CJ., et al. 1977. Clin Chem. 23: 593-5. PMID: 837549
- Simultaneous determination of phenytoin and carbamazepine in human hair by high-performance liquid chromatography. | Mei, Z. and Williams, J. 1997. Ther Drug Monit. 19: 92-4. PMID: 9029755
- Chemical ionization mass spectrometry for rapid assay of drugs in serum. | Lehrer, M. and Karmen, A. 1976. J Chromatogr. 126: 615-23. PMID: 977699
- A simple test to characterise C8/C18-bonded phases, particularly for toxicological screening | T. Daldrup & B. Kardel. 1984. Chromatographia volume. 18: 81–83.
- Rapid Determination of Bupropion in Human Plasma by High Performance Liquid Chromatography | Khalil I. Al-khamis. 1989. Journal of Liquid Chromatography. Volume 12, Issue 4: 645-655.
- Reversed-phase high-performance liquid chromatographic separation of potato glycoalkaloids and hydrolysis products on acidic columns | Mendel. Friedman and Carol E. Levin. 1992. J. Agric. Food Chem. 40, 11: 2157–2163.
- A Capillary GC Method Using Nitrogen Phosphorus Detection for Determination of Topiramate in Patients with Epilepsy | J. Malakova, H. Brozmanova, V. Vorisek, V. Prochazkova & V. Palicka. 2007. Chromatographia. 66: 363–367.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-(p-Methylphenyl)-5-phenylhydantoin, 25 mg | sc-210245 | 25 mg | $260.00 |