Molecular structure of 5-OxoETE-d7
5-OxoETE-d7
Alternate Names:
5-KETE-d7
Molecular Weight:
325.5
Molecular Formula:
C20H23D7O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5-OxoETE-d7 contains seven deuterium atoms at 6, 8, 9, 11, 12, 14, and 15 positions. It is used as an internal standard for the quantification of 5-oxoETE by GC- or LC-mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils(1). It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM(2). 5-OxoETE. This selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils(3,4).
5-OxoETE-d7 References
1 Powell, W.S., Gravelle, F., Gravel, S. Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J Biol Chem 267 19233-19241 (1992). 2 Powell, W.S.,Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-OxoETE-d7, 25 µg | sc-221043 | 25 µg | $177.00 | |||
5-OxoETE-d7, 50 µg | sc-221043A | 50 µg | $337.00 |