Date published: 2026-3-19

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5-O-Benzyl-D-ribose (CAS 72369-89-2)

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CAS Number:
72369-89-2
Molecular Weight:
240.25
Molecular Formula:
C12H16O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-O-Benzyl-D-ribose is a chemical compound that has found significant utility in various research fields, particularly in carbohydrate chemistry and nucleoside synthesis. As a ribose derivative, it has been utilized as a building block in the synthesis of nucleoside analogs and nucleotide derivatives for studying RNA and DNA biochemistry. This compound serves as a key intermediate in the synthesis of modified nucleosides, which are valuable tools for probing nucleic acid structure and function, as well as for the development of nucleoside-based research and antiviral agents. Additionally, 5-O-Benzyl-D-ribose has been employed in the preparation of carbohydrate-based ligands and glycosylation reactions, contributing to the advancement of glycobiology and carbohydrate chemistry research. Its ability to undergo selective functionalization at the 5′ position makes it a versatile starting material for the synthesis of diverse ribose-modified compounds with tailored properties. Furthermore, this compound has been investigated for its potential applications in supramolecular chemistry and materials science, where it may serve as a component in the design and fabrication of novel biomaterials and molecular assemblies.


5-O-Benzyl-D-ribose (CAS 72369-89-2) References

  1. Nucleophilic displacement reactions in carbohydrates. Part X. The solvolysis of benzyl 5-O-p-bromophenylsulphonyl-2, 3-O-isopropylidene-β-D-ribofuranoside: a benzyloxy-group migration.  |  Brimacombe, J. S., and O. A. Ching. 1969. Journal of the Chemical Society C: Organic. 6: 964-967.
  2. Synthesis of four stereoisomers of 4-amino-2-(hydroxymethyl) tetrahydrofuran-4-carboxylic acid  |  Yoshimura, Juji, et al. 1982. Carbohydrate Research. 99: 129-142.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-O-Benzyl-D-ribose, 500 mg

sc-221039
500 mg
$380.00